4-AMINOPYRIMIDINE-5-CARBONITRILE

Product Name:4-AMINOPYRIMIDINE-5-CARBONITRILE
CAS:16357-69-0
MFC5H4N4
MW:120.11
EINECS:
MOL File:16357-69-0.mol

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4-Aminopyrimidine-5-carbonitrile: Technical Overview and Applications

1. Product Specifications

Parameter Value
CAS Number 16357-69-0
Molecular Formula C5H4N4
Molecular Weight 120.12 g/mol
Purity ≥97%
Synonyms 4-Amino-5-cyanopyrimidine, 5-Cyano-4-aminopyrimidine

Structural Note: The compound features an amino group (-NH2) at position 4 and a nitrile group (-CN) at position 5 on the pyrimidine ring, distinguishing it from positional isomers like 2-aminopyrimidine-5-carbonitrile (CAS 1753-48-6).

2. Key Applications

  • Pharmaceutical Intermediates: Critical in synthesizing kinase inhibitors and antiviral agents.
  • Agrochemicals: Used to develop herbicides with targeted action mechanisms.
  • Material Science: Serves as a precursor for nitrogen-rich polymers.

3. Comparative Analysis

Compound CAS Number Substitution Pattern Molecular Formula
4-Aminopyrimidine-5-carbonitrile 16357-69-0 4-NH2, 5-CN C5H4N4
2-Aminopyrimidine-5-carbonitrile 1753-48-6 2-NH2, 5-CN C5H4N4
4-Aminopyrimidine 591-54-8 4-NH2 C4H5N3

Note: Substitution position significantly impacts reactivity and application suitability.

4. Usage Guidelines

Storage Recommendations

  • Store in airtight containers at 2-8°C
  • Protect from moisture and direct sunlight

Safety Protocols

  • Use PPE (gloves, goggles) during handling
  • Avoid inhalation of dust particles

5. Industry Case Studies

Case Study 1: Antiviral Drug Development

Client: European Pharma Research Consortium
Application: Intermediate in nucleoside analogue synthesis
Outcome: Achieved 92% yield in final API synthesis

Case Study 2: Specialty Polymer Production

Client: Advanced Materials Inc. (USA)
Application: Precursor for high-temperature resins
Outcome: Developed polymer with 320°C thermal stability

6. Contact Information

For technical specifications or bulk inquiries:
Email: info@vivalr.com
Tel: (86) 15866781826

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