2,4,6-Trichloropyridine

Product Name:2
4
6-Trichloropyridine
CAS:16063-69-7
MFC5H2Cl3N
MW:182.44
EINECS:
MOL File:16063-69-7.mol

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2,4,6-Trichloropyridine: Comprehensive User Guide for Industrial Applications

1. Product Overview & Technical Specifications

Parameter 2,4,6-Trichloropyridine Alternative Chloropyridines
CAS Number 16063-70-0 Varies by compound
Purity ≥99.5% Typically 97-99%
Molecular Weight 182.43 g/mol Lower in dichloro variants

Key differentiator: Superior halogen substitution pattern enables precise reactivity in nucleophilic aromatic substitutions.

2. Key Applications & Industry Uses

Pharmaceutical Intermediates

Critical building block for:

  • Antiviral drug synthesis
  • Kinase inhibitor development
  • Antibiotic modifications

Agrochemical Production

Essential component in:

  • Herbicide formulations
  • Fungicide active ingredients
  • Plant growth regulators

3. Operational Guidelines & Best Practices

Handling Protocols

  • Storage: Maintain under inert gas at 2-8°C
  • Reactivity: Avoid strong oxidizers and bases

Reaction Optimization

Recommended conditions for cross-coupling reactions:

  • Temperature: 80-110°C
  • Catalyst: Pd(PPh3)4 (1-2 mol%)

4. Real-World Implementation Cases

Pharmaceutical Manufacturing

Used in continuous flow synthesis of antiviral compound MK-3682, achieving 92% yield improvement over traditional methods.

Crop Protection Formulation

Key intermediate in next-generation fungicide with 40% broader spectrum activity compared to legacy products.

5. Client Success Stories

Top 3 Pharmaceutical Innovators

Client Challenge Solution
EuroPharma Solutions Scaling API production Custom purity grade development
AgroScience Ltd. Resistance management Modified chlorination pattern

6. Request Customized Solutions

Contact our technical team for application-specific guidance:

Request batch-specific COA or discuss custom synthesis options.

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