3-BROMO-4-CHLORO-5-NITROPYRIDINE

Comprehensive Guide to 3-Bromo-4-Chloro-5-Nitropyridine

Table of Contents

• 1. Product Overview & Specifications
• 2. Key Applications & Industrial Uses
• 3. Usage Guidelines & Safety Protocols
• 4. Synthesis Case Studies
• 5. Verified Customer Implementations
• 6. Request Customized Quotation

1. Product Overview & Specifications

3-Bromo-4-Chloro-5-Nitropyridine (CAS 134545-89-6) is a halogenated nitropyridine derivative with molecular formula C₅H₂BrClN₂O₂ and molecular weight 256.44 g/mol.

2. Key Applications & Industrial Uses

Critical applications include:

• Pharmaceutical Intermediates: Synthesis of kinase inhibitors and antiviral agents
• Agrochemicals: Building block for next-gen herbicides
• Material Science: Precursor for conductive polymers

3. Usage Guidelines & Safety Protocols

Handling Recommendations:

• Use NIOSH-approved respirator with N95 filters
• Maintain reaction temperature below 40°C
• Store under nitrogen atmosphere

4. Synthesis Case Studies

Case 1: Suzuki-Miyaura Coupling

Successful coupling with 4-methoxyphenylboronic acid using Pd(PPh₃)₄ catalyst (85% yield)

5. Verified Customer Implementations

Customer 1: European Pharma Leader

• Application: EGFR inhibitor development
• Scale: 150kg batch production
• Result: 92% purity in final API

Customer 2: US Material Research Institute

• Application: Organic semiconductor synthesis
• Scale: 25kg pilot project
• Result: Achieved conductivity of 15 S/cm

6. Request Customized Quotation

Contact our technical team for:

• Batch-specific COA
• Custom synthesis solutions
• Bulk pricing (50kg+ orders)

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