2-Amino-5-chloro-3-nitropyridine: Comprehensive Guide for Industrial Buyers & Researchers
Contents
- 1. Product Specifications & Comparative Analysis
- 2. Key Applications & Industrial Use Cases
- 3. Operational Guidelines & Safety Protocols
- 4. Real-World Application Case Studies
- 5. Client Success Stories
- 6. Request Customized Quotation
1. Product Specifications & Comparative Analysis
| Parameter | 2-Amino-5-chloro-3-nitropyridine | 2-Amino-3-nitropyridine | 5-Chloro-3-nitropyridine |
|---|---|---|---|
| CAS Number | 54231-36-6 | 21203-68-9 | 22353-26-8 |
| Molecular Formula | C5H4ClN3O2 | C5H5N3O2 | C5H3ClN2O2 |
| Purity Grade | ≥99% (HPLC) | ≥98% | ≥97% |
| Thermal Stability | Stable up to 200°C | Decomposes at 180°C | Stable up to 190°C |
2. Key Applications & Industrial Use Cases
Pharmaceutical Intermediate
Critical component in synthesis of:
- Antibacterial agents (e.g., fluoroquinolone derivatives)
- Kinase inhibitors for cancer therapeutics
- Neurological disorder medications
Agrochemical Applications
- Key precursor for systemic fungicides
- Herbicide intermediate with enhanced leaf penetration
- Insect growth regulator formulations
3. Operational Guidelines & Safety Protocols
| Parameter | Specification |
|---|---|
| Storage Conditions | 2-8°C in inert atmosphere (N2 or Argon) |
| Handling Requirements | Use Class IIB ventilated enclosure |
| Incompatible Materials | Strong oxidizers, concentrated acids |
4. Real-World Application Case Studies
Case 1: Antibiotic Production Scale-Up
Challenge: Improve yield in ciprofloxacin precursor synthesis
Solution: Optimized nitration sequence using 2-Amino-5-chloro-3-nitropyridine
Result: 22% yield increase with 99.3% purity
Case 2: Next-Gen Herbicide Development
Challenge: Create residual activity in clay soils
Solution: Chloropyridine-based formulation
Result: 8-week soil persistence achieved
5. Client Success Stories
PharmaCorp Solutions (Germany)
“Consistent ≥99.5% purity enabled first-pass API approval with EMA”
AgroNova Ltd (Brazil)
“Custom particle size distribution improved formulation stability in tropical climates”
6. Request Customized Quotation
Contact our technical team for:
- Bulk pricing (100kg+ quantities)
- GMP-certified batches
- Custom synthesis protocols
Email: info@vivalr.com
Phone: (86) 15866781826


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