3-Fluoro-2-hydroxypyridine Product Guide
Table of Contents
- Product Specifications & Comparative Analysis
- Applications & Functional Characteristics
- Implementation Scenarios
- Client Success Stories
- Consultation & Procurement
1. Product Specifications & Comparative Analysis
| Parameter | 3-Fluoro-2-hydroxypyridine | Conventional Pyridine Derivatives |
|---|---|---|
| CAS Number | 1547-29-1 | Varies (e.g., 372-47-4 for 3-Fluoropyridine) |
| Molecular Formula | C5H4FNO | C5H5N derivatives |
| Molecular Weight | 113.09 g/mol | 79.10-129.54 g/mol |
| Density | 1.661 g/cm³ | 0.982-1.9 g/cm³ |
| Boiling Point | 255.8°C at 760 mmHg | 115-242°C |
| Topological Polar Surface Area | 29.1 Ų | 12.4-33.1 Ų |
2. Applications & Functional Characteristics
This fluorinated pyridine derivative serves as a critical intermediate in:
- Pharmaceutical synthesis (API development)
- Agrochemical research (pesticide precursors)
- Ligand design for catalytic systems
- Positron Emission Tomography (PET) tracer development
Key functional advantages include:
- Enhanced electron-withdrawing capacity vs non-fluorinated analogs
- Improved metabolic stability in drug candidates
- Precise regiochemical control in heterocyclic reactions
3. Implementation Scenarios
Scenario 1: Radiolabeled Compound Synthesis
Used in the production of 18F-labeled PET tracers through nucleophilic aromatic substitution, enabling non-invasive diagnostic imaging.
Scenario 2: Nicotinic Receptor Targeting
Structural component in neurological research compounds targeting α4β2 nicotinic acetylcholine receptors.
4. Client Success Stories
Case Study 1: Pharmaceutical Innovator (Confidential)
- Application: Development of smoking cessation therapeutics
- Outcome: 40% improvement in receptor binding affinity vs previous lead compounds
- Scale: 50kg batch production with ≥99.5% purity
Case Study 2: Agrochem Leader
- Application: Fungicide intermediate optimization
- Result: 25% increase in field efficacy through improved compound stability
- Technical Support: Customized purification protocol development
5. Consultation & Procurement
For technical specifications, bulk pricing, or custom synthesis requirements:
Email: info@vivalr.com
Tel: +86 158 6678 1826
Submit your project requirements for:
- Batch-specific analytical certificates (COA)
- Regulatory documentation support
- Custom fluorination services
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