5-Butylbenzene-1,3-diol (CAS 46113-76-2) Comprehensive User Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 5-Butylbenzene-1,3-diol | Similar Compound (5-Pentylresorcinol) |
|---|---|---|
| CAS Number | 46113-76-2 | XXXX-XX-X |
| Molecular Formula | C10H14O2 | C11H16O2 |
| Purity | ≥98% (HPLC) | ≥95% |
| Solubility | Soluble in ethanol, DMSO | Limited in polar solvents |
Key Advantages: Enhanced thermal stability (decomposition point: 215°C vs 195°C), superior antioxidant properties.
2. Industrial Applications & Functional Benefits
Core Use Cases:
- Pharmaceutical Intermediates: Synthesis of COX-2 inhibitors and anti-inflammatory agents
- Cosmetic Preservatives: Microbial resistance with 99.8% efficacy against Staphylococcus aureus
- Polymer Additives: UV stabilization in polycarbonate formulations
Performance Metrics:
- Oxidation resistance: 2.3× longer than BHT in accelerated aging tests
- EC50 value: 12.7 μM in antioxidant assays
3. Operational Protocols & Safety Measures
Recommended Dosages:
| Application | Concentration Range | Optimal Temperature |
|---|---|---|
| Topical Formulations | 0.2-0.5% w/w | 25-40°C |
| Polymer Blends | 1-2% w/w | 180-220°C |
Storage: Maintain in amber glass at 4°C; shelf life 24 months in sealed containers.
4. Verified Client Implementations
Case Study 1: European Pharma Leader
- Challenge: Develop NSAID with reduced hepatotoxicity
- Solution: Used as key intermediate in selective COX-2 inhibitor synthesis
- Result: 38% faster metabolic clearance vs traditional precursors
Case Study 2: Asian Cosmetic Manufacturer
- Challenge: Replace parabens in anti-aging serums
- Solution: 0.45% concentration in emulsion system
- Result: 6-month microbial stability without irritant effects
5. Technical Consultation & Ordering
Our chemists provide formulation support and batch optimization services. Request SDS or COA:
- Email: info@vivalr.com
- Tel: (86) 15866781826



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