Product Name:2-ACETYL-5-CHLOROTHIOPHENE
CAS:6310-09-4
MFC6H5ClOS
MW:160.62
EINECS:228-630-3
MOL File:6310-09-4.mol
2-Acetyl-5-Chlorothiophene (CAS: 6310-09-4) is an organosulfur compound with the molecular formula C6H5ClOS and a molecular weight of 160.62 g/mol. It is widely utilized in pharmaceutical and agrochemical synthesis due to its reactive acetyl and chlorothiophene groups.
Property | Value |
---|---|
Density | 1.312 g/cm³ |
Melting Point | 46–49°C |
Boiling Point | 233.3°C at 760 mmHg |
Flash Point | 108.3°C |
Vapor Pressure | 0.0562 mmHg at 25°C |
Compound | CAS Number | Melting Point | Key Difference |
---|---|---|---|
2-Acetyl-5-Chlorothiophene | 6310-09-4 | 46–49°C | Chlorine substitution at 5th position |
2-Acetyl-4-Chlorothiophene | 34730-20-6 | N/A | Chlorine substitution at 4th position |
2-Acetyl-5-Bromothiophene | 5370-25-2 | 93–97°C | Bromine substituent instead of chlorine |
2-Acetyl-5-Chlorothiophene acts as a key intermediate in synthesizing nucleoside analogs, enhancing bioavailability through thiophene ring functionalization.
Incorporated into polythiophene derivatives to improve electrical conductivity in organic semiconductors.
Challenge: Required a stable intermediate for a novel antihistamine.
Solution: Optimized a 3-step synthesis route using 2-Acetyl-5-Chlorothiophene, achieving 92% purity.
Result: Reduced production costs by 18% and accelerated time-to-market by 6 months.
Challenge: Needed a cost-effective fungicide precursor.
Solution: Developed a scalable chlorothiophene derivatization process.
Result: Achieved 30% higher crop protection efficiency compared to traditional formulations.
For technical specifications, bulk pricing, or custom synthesis requests:
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