Product Name:2-Chloropyrimidine
CAS:1722-12-9
MFC4H3ClN2
MW:114.53
EINECS:217-020-2
MOL File:1722-12-9.mol
Parameter | 2-Chloropyrimidine | 2-Bromopyrimidine | Pyrimidine |
---|---|---|---|
CAS Number | 19762-37-7 | 4595-60-2 | 289-95-2 |
Molecular Formula | C4H3ClN2 | C4H3BrN2 | C4H4N2 |
Purity Grade | ≥99% (HPLC) | ≥98% | ≥99.5% |
Melting Point | 34-36°C | 41-43°C | 20-22°C |
Enables synthesis of antiviral agents (HCV, HIV inhibitors) through nucleophilic substitution reactions.
Key precursor for pyrethroid insecticides and fungicide development via Suzuki coupling reactions.
Building block for liquid crystals and OLED materials with enhanced electron-transport properties.
Process: Palladium-catalyzed cross-coupling with boronic acids (80% yield)
Process: Nucleophilic aromatic substitution with amines (75% efficiency)
Application: HCV protease inhibitor intermediate
Result: 22% yield improvement vs. brominated analog
Application: Systemic fungicide production
Result: 15% cost reduction in synthesis pathway
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