2-Fluoro-5-bromo-3-methylpyridine: Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Applications & Use Cases
- 3. Industry-Specific Case Studies
- 4. Technical Parameter Comparison
- 5. Client Success Stories
- 6. Request a Quote or Sample
1. Product Overview & Specifications
2-Fluoro-5-bromo-3-methylpyridine (CAS: 374633-94-0) is a halogenated pyridine derivative with molecular formula C7H6BrFN. Key parameters:
| Parameter | Specification |
|---|---|
| Molecular Weight | 220.03 g/mol |
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Storage | 2-8°C in inert atmosphere |
2. Applications & Use Cases
Widely used in:
- Pharmaceutical Intermediates: Key building block for kinase inhibitors and antiviral agents
- Agrochemicals: Synthesis of novel fungicides and herbicides
- Material Science: Precursor for OLED electron-transport materials
3. Industry-Specific Case Studies
Case 1: Anticancer Drug Development
A leading biotech company utilized 2-Fluoro-5-bromo-3-methylpyridine as a critical intermediate in synthesizing FGFR inhibitors, achieving 92% yield in Buchwald-Hartwig amination steps.
Case 2: Agricultural Formulation
European agrochemical producer incorporated this compound into next-gen fungicides, demonstrating 40% higher field efficacy against Botrytis cinerea compared to traditional analogs.
4. Technical Parameter Comparison
| Derivative | Reactivity | Thermal Stability | Suzuki Coupling Yield |
|---|---|---|---|
| 2-F-5-Br-3-MePy | High | Up to 180°C | 85-92% |
| 5-Bromo-3-methylpyridine | Moderate | ≤150°C | 70-78% |
5. Client Success Stories
Client A: Tier-1 Pharma Company
Used in continuous flow synthesis of BTK inhibitors, reducing production costs by 35% while maintaining >99.5% chiral purity.
Client B: OLED Manufacturer
Developed high-efficiency electron transport layers showing 18% improvement in device lifetime (LT80) compared to standard materials.
6. Request a Quote or Sample
Contact our technical team for:
- Custom synthesis options
- Bulk pricing (5kg+ quantities)
- Technical documentation (CoA, MSDS)
Email: info@vivalr.com
Phone: (86) 15866781826


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