2-Bromo-3-chloropyridine

Product Name:2-Bromo-3-chloropyridine
CAS:96424-68-9
MFC5H3BrClN
MW:192.44
EINECS:678-771-3
MOL File:96424-68-9.mol

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2-Bromo-3-chloropyridine: Comprehensive User Guide

1. Product Overview & Specifications

2-Bromo-3-chloropyridine (CAS 134149-36-3) is a halogenated pyridine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters:

Parameter Specification Competitor A Competitor B
Purity ≥99.5% ≥98% ≥97.5%
Appearance White crystalline powder Off-white powder Yellowish tint
Moisture Content <0.1% 0.5% 0.8%

2. Key Applications

Pharmaceutical Intermediate

Used in synthesis of kinase inhibitors and antiviral agents due to its optimal halogen positioning for Suzuki coupling reactions.

Agrochemical Production

Critical component in next-generation fungicides, with 30% higher bioactivity compared to traditional chloropyridine derivatives.

3. Usage Scenarios

Scenario 1: API Synthesis

Step 1: Dissolve 2-Bromo-3-chloropyridine (1.0 eq) in anhydrous THF under N₂ atmosphere
Step 2: Add Pd(PPh₃)₄ catalyst (0.05 eq) and boronic acid (1.2 eq)
Yield: 82-88% (vs. 75% industry average)

4. Client Case Studies

Case Study 1: Top 10 Pharma Company

Challenge: Improve yield in JAK2 inhibitor synthesis
Solution: Implemented our ≥99.5% purity grade
Result: 18% yield increase with 40% reduction in purification steps

Case Study 2: Agrochemical Leader

Challenge: Develop low-residue fungicide
Solution: Used as key building block in novel compound
Result: Achieved EPA approval 5 months faster than competitors

5. Request Quotation

Email: info@vivalr.com
Phone: (86) 15866781826

Request batch-specific COA or discuss custom synthesis options.

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