2-Bromo-3-chloropyridine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
2-Bromo-3-chloropyridine (CAS 134149-36-3) is a halogenated pyridine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters:
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥99.5% | ≥98% | ≥97.5% |
| Appearance | White crystalline powder | Off-white powder | Yellowish tint |
| Moisture Content | <0.1% | 0.5% | 0.8% |
2. Key Applications
Pharmaceutical Intermediate
Used in synthesis of kinase inhibitors and antiviral agents due to its optimal halogen positioning for Suzuki coupling reactions.
Agrochemical Production
Critical component in next-generation fungicides, with 30% higher bioactivity compared to traditional chloropyridine derivatives.
3. Usage Scenarios
Scenario 1: API Synthesis
Step 1: Dissolve 2-Bromo-3-chloropyridine (1.0 eq) in anhydrous THF under N₂ atmosphere
Step 2: Add Pd(PPh₃)₄ catalyst (0.05 eq) and boronic acid (1.2 eq)
Yield: 82-88% (vs. 75% industry average)
4. Client Case Studies
Case Study 1: Top 10 Pharma Company
Challenge: Improve yield in JAK2 inhibitor synthesis
Solution: Implemented our ≥99.5% purity grade
Result: 18% yield increase with 40% reduction in purification steps
Case Study 2: Agrochemical Leader
Challenge: Develop low-residue fungicide
Solution: Used as key building block in novel compound
Result: Achieved EPA approval 5 months faster than competitors
5. Request Quotation
Email: info@vivalr.com
Phone: (86) 15866781826
Request batch-specific COA or discuss custom synthesis options.


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