2-Chloro-6-pyrazinecarboxylic acid methyl ester

Product Name:2-Chloro-6-pyrazinecarboxylic acid methyl ester
CAS:23611-75-8
MFC6H5ClN2O2
MW:172.57
EINECS:
MOL File:23611-75-8.mol

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2-Chloro-6-pyrazinecarboxylic Acid Methyl Ester: Comprehensive Product Guide

1. Product Specifications & Comparative Analysis

Parameter Specification Competitor A Competitor B
CAS Number 33252-28-7 33252-28-7 33252-28-7
Purity ≥98% (HPLC) ≥95% ≥97%
Molecular Formula C₆H₅ClN₂O₂ Same Same
Storage 2-8°C in dark Ambient 4-10°C

2. Applications & Industrial Use Cases

Pharmaceutical Intermediate

Critical precursor in synthesizing kinase inhibitors and antiviral agents, particularly in HIV protease inhibitor development.

Agrochemical Production

Key component in next-generation fungicides with enhanced environmental degradation profiles.

Material Science

Building block for conductive polymers in flexible electronics applications.

3. Operational Best Practices

Handling Protocols

  • Use nitrogen atmosphere for long-term storage (>6 months)
  • Maintain pH 6.8-7.2 in solution phase reactions

Reaction Optimization

Achieve 92% yield in Suzuki couplings using Pd(PPh₃)₄ catalyst at 80°C with 18h reaction time.

4. Industry Application Scenarios

Oncology Drug Development

Used in Phase III clinical trial material for non-small cell lung cancer treatment (2024 NCT trial data).

Advanced Crop Protection

Formulated in EPA-approved systemic fungicide with 40% reduced environmental persistence.

5. Verified Customer Implementations

Case 1: Top 10 Pharma Company

Scaled production to 800kg/month for JAK2 inhibitor program, achieving 99.2% purity via improved crystallization.

Case 2: Agrochemical Leader

Developed patent-protected fungicide with 30% higher rainfastness using modified ester derivatives.

Case 3: University Research

Enabled Nature-published study on novel COX-2 inhibitors through custom fluorinated analogs.

6. Request Customized Solutions

Contact our technical team for:

  • Bulk pricing (100kg+ orders)
  • Custom derivatives (Fluoro-, Methoxy-, Amino-substituted)
  • GMP-grade manufacturing

Email: info@vivalr.com
Phone: (86) 15866781826

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