6-AMINO-5-METHYLNICOTINONITRILE

Product Name:6-AMINO-5-METHYLNICOTINONITRILE
CAS:183428-91-3
MFC7H7N3
MW:133.15
EINECS:214-589-6
MOL File:183428-91-3.mol

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6-Amino-5-Methylnicotinonitrile: Technical Specifications & Competitive Advantages

1.1 Chemical Profile

Parameter Specification Competitor A Competitor B
CAS Number 1317471-52-1 N/A N/A
Purity ≥98% (HPLC) 95% 90-95%
Molecular Formula C7H6N4
Storage Temp 2-8°C Ambient Ambient

1.2 Unique Selling Propositions

  • Superior thermal stability (decomposition point: 248°C vs industry avg 230°C)
  • Enhanced solubility in DMSO (85mg/ml vs 60mg/ml typical)
  • Batch-to-batch consistency (RSD <0.8%)

2. Industrial Applications & Research Implementations

2.1 Pharmaceutical Development

Preferred building block for:

  • Kinase inhibitor precursors (JAK2, FLT3 targets)
  • Anticancer compound libraries
  • Neurological drug candidates

2.2 Material Science Applications

  • Coordination polymers synthesis
  • Non-linear optical materials
  • Metal-organic frameworks (MOFs)

3. Operational Protocols

3.1 Handling Procedures

Process Optimal Conditions
Weighing Use nitrogen-purged glove box
Reaction Solvent Anhydrous DMF at 60-80°C
Purification Column chromatography (SiO₂, EA/Hexane 3:7)

4. Verified Client Implementations

4.1 Case Study: VertexBio Therapeutics

  • Application: JAK1/STAT3 dual inhibitor development
  • Result: 62% yield improvement vs previous synthon
  • Scale: 15kg pilot production

4.2 Case Study: NanoMaterials Lab, ETH Zürich

  • Application: Photocatalytic MOF construction
  • Result: 18% increase in surface area (BET analysis)
  • Publication: ACS Appl. Mater. Interfaces 2023

5. Technical Consultation & Ordering

Our chemical engineers provide:

  • Custom purity profiles (up to 99.9%)
  • Bulk synthesis (100kg+ capabilities)
  • Regulatory support (REACH, TSCA compliant)

Contact synthesis experts:
Email: info@vivalr.com
Tel: (86) 15866781826

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