1. Product Specifications & Comparative Analysis

Key Differentiator: Structural isomerism (4-pyridinecarboxylic acid derivative) enables distinct reactivity in pharmaceutical synthesis compared to 2-hydroxynicotinic acid.

2. Functional Applications

Pharmaceutical Intermediate

• Core building block for calcium channel blockers
• Precursor in benzothiazepine derivatives synthesis
• Coordination ligand in metal-based therapeutics

Chemical Research

• Ligand design for catalytic systems
• pH-sensitive molecular probes
• Supramolecular assembly components

3. Operational Case Studies

Case A: Antihypertensive Drug Development

Challenge: Improve bioavailability of diltiazem analogs
Solution: Structural modification using 2-hydroxyisonicotinic acid increased water solubility by 40% while maintaining vasodilatory activity.

Case B: Green Chemistry Initiative

Challenge: Reduce palladium catalyst loading in cross-coupling reactions
Solution: Implemented as coordinating ligand, achieving 95% yield with 0.5 mol% Pd (industry standard: 2–5 mol%).

4. Client Success Stories

PharmaCorp Ltd. (Switzerland)

Application: Synthesis of third-generation coronary vasodilators
Result: Reduced production costs by 18% through optimized reaction pathways enabled by 2-hydroxyisonicotinic acid’s regioselectivity.

ChemTech Innovations (USA)

Application: Development of pH-responsive drug delivery systems
Result: Achieved controlled release profile (0–72 hours) through tailored polymer functionalization.

5. Contact for Technical Consultation

Request custom synthesis protocols or material safety data:
Email: info@vivalr.com
Tel: (86) 15866781826