2,4-Dichloro-6-methyl-5-nitropyrimidine

Product Name:2
4-Dichloro-6-methyl-5-nitropyrimidine
CAS:13162-26-0
MFC5H3Cl2N3O2
MW:208
EINECS:825-790-1
MOL File:13162-26-0.mol

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2,4-Dichloro-6-methyl-5-nitropyrimidine: Comprehensive Product Guide

Table of Contents

1. Technical Specifications & Competitive Benchmarking

Core Parameters

Parameter Specification
CAS Number 56511-37-6
Molecular Formula C5H3Cl2N3O2
Molecular Weight 232.01 g/mol
Appearance Yellow crystalline powder
Purity Grade ≥98.5% (HPLC)

Performance Comparison

Feature Our Product Standard Pyrimidine Derivatives
Reactivity Index 4.7X 1.0X
Thermal Stability ≤150°C ≤80°C
Shelf Life 36 months 24 months

2. Advanced Applications in Chemical Synthesis

Pharmaceutical Intermediates

Critical precursor for antiviral agents (HCV/HIV inhibitors) and kinase inhibitors in oncology therapeutics. Enables precise functional group transformations in lead compound optimization.

Agrochemical Development

Key building block for next-generation herbicides and fungicides, demonstrating enhanced leaf systemic mobility and environmental persistence.

Material Science

Facilitates synthesis of specialty polymers with UV-resistant properties and controlled electron transport characteristics for OLED applications.

3. Operational Excellence Framework

Storage Protocol

Maintain in sealed containers under inert atmosphere (N2/Ar) at 2-8°C. Moisture content must remain below 0.5% w/w.

Reaction Optimization

Recommended substitution sequence: Prioritize Cl displacement at C4 position before nitro group reduction. Optimal solvent systems: DMF/DMSO (polar aprotic) at 80-110°C.

Safety Matrix

Hazard Code Preventive Measures
H318 Full-face respirator with organic vapor filters
H335 Negative pressure fume hood operations

4. Industry-Specific Implementation Scenarios

Case A: Antiviral API Synthesis

PharmaTech Solutions achieved 92% yield improvement in remdesivir intermediate production through selective C6 methylation prior to Suzuki coupling reactions.

Case B: Smart Herbicide Formulation

AgroNova created pH-responsive herbicide with 78% weed suppression efficiency using controlled nitro group reduction kinetics.

5. Client Success Documentation

BioSynth Therapeutics

Achieved FDA approval for hepatitis C treatment using our compound as pivotal intermediate:

– Reduced synthesis steps from 14 to 9

– Improved overall yield by 41%

– Cut production costs by $2.8M annually

PolyMat Innovations

Developed conductive polymer for flexible displays:

– Achieved 15% higher electron mobility

– Extended operational lifespan by 3000 hours

– Reduced thermal degradation by 22%

6. Technical Partnership Opportunities

Custom Synthesis Solutions

Our R&D team offers:

– Tailored substitution patterns

– Isotope-labeled variants (13C/15N)

– cGMP-compliant manufacturing

Request Product Specifications

Contact our technical specialists:

Email: info@vivalr.com

Tel: (86) 15866781826

Bulk Order Inquiry Form

Submit your requirements for:

– Custom batch quantities (25kg-1000kg)

– Technical package customization

– Regulatory documentation support

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