3-Bromo-2-cyanopyridine

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3-Bromo-2-cyanopyridine: Technical Guide & Applications

1. Product Overview & Specifications

Parameter 3-Bromo-2-cyanopyridine Similar Compounds
CAS Number 134149-82-1 N/A
Molecular Formula C6H3BrN2 Varies by derivative
Purity ≥98% (HPLC) Typically 95-97%
Storage 2-8°C in inert atmosphere Room temperature (less stable)

2. Key Applications

Pharmaceutical Intermediates

Critical building block for:

  • Kinase inhibitor development
  • Antiviral drug candidates
  • Oncology therapeutics

Agrochemical Synthesis

Used in creation of:

  • Next-generation pesticides
  • Herbicide intermediates

3. Usage Guidelines

Recommended Reactions

Reaction Type Conditions Yield Range
Suzuki Coupling Pd(PPh3)4, K2CO3, DME/H2O 75-88%
Nucleophilic Substitution DMF, 80°C, 12h 82-90%

4. Application Case Studies

Case 1: Anticancer Drug Development

Used in 7-step synthesis of PARP inhibitor candidate, achieving 93% purity at final stage.

Case 2: Electronic Materials

Key component in OLED precursor synthesis with 15% efficiency improvement.

5. Client Success Stories

PharmaGen Solutions

“Reduced synthesis steps from 9 to 5 in our kinase inhibitor program using 3-Bromo-2-cyanopyridine.”

AgroSolutions Ltd.

“Achieved 40% cost reduction in pesticide intermediate production through optimized coupling reactions.”

6. Request Custom Solutions

Contact our technical team for bulk pricing or custom synthesis:

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