4-Chloro-3-pyridinesulfonamide: Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industry Uses
- 3. Operational Guidelines & Safety
- 4. Comparative Analysis with Similar Compounds
- 5. Real-World Use Cases
- 6. Customer Success Stories
- 7. Request Customized Quotes
1. Product Overview & Specifications
4-Chloro-3-pyridinesulfonamide (CAS 144330-52-3) is a high-purity sulfonamide derivative extensively used in pharmaceutical and agrochemical synthesis.
| Parameter | Specification |
|---|---|
| Molecular Formula | C5H5ClN2O2S |
| Molecular Weight | 192.63 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥99% |
| Melting Point | 218-222°C |
| Storage | 2-8°C in dry environment |
2. Key Applications & Industry Uses
Pharmaceutical Intermediate
Critical component in kinase inhibitor development for cancer therapeutics
Agrochemical Synthesis
Building block for novel sulfonylurea-class herbicides
Chemical Research
Precursor in organocatalyst development and coordination chemistry
3. Operational Guidelines & Safety
| Parameter | Requirement |
|---|---|
| Handling | Use NIOSH-approved respirator & chemical gloves |
| Solubility | DMSO: 50 mg/mL; Water: <1 mg/mL |
| Incompatibilities | Strong oxidizers, concentrated acids |
4. Comparative Analysis
| Compound | Reactivity | Cost Efficiency | Thermal Stability |
|---|---|---|---|
| 4-Chloro-3-pyridinesulfonamide | High | ★★★★☆ | 220°C |
| 3-Chloro isomer | Medium | ★★★☆☆ | 205°C |
| 4-Fluoro analog | Low | ★★☆☆☆ | 195°C |
5. Real-World Use Cases
Case 1: Anticancer Drug Development
Used as key intermediate in third-generation EGFR inhibitors showing 92% yield improvement
Case 2: Herbicide Formulation
Enabled 40% cost reduction in sulfonylurea herbicide production for major agrochemical company
6. Customer Success Stories
PharmaTech Innovations
Reduced lead compound synthesis time from 14 to 6 days using our GMP-grade material
AgroSolutions Ltd.
Achieved 99.7% purity in final herbicide product using our optimized sulfonamide derivatives
7. Request Customized Quotes
Contact our technical team for batch-specific COA and volume pricing:
Email: info@vivalr.com
Phone: (86) 15866781826
★ Bulk Order Discount: 15% off orders >50kg ★
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