2-Methoxy-3-fluoro-5-bromopyridine

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2-Methoxy-3-fluoro-5-bromopyridine: Comprehensive Product Guide

Table of Contents

Product Overview & Specifications

CAS Number: 126150-90-3

Molecular Formula: C6H4BrFNO

Molecular Weight: 220.01 g/mol

Purity: ≥98% (HPLC)

Comparative Analysis

Property 2-Methoxy-3-fluoro-5-bromopyridine Similar Compounds
Reactivity High bromine substitution activity Lower in non-halogenated analogs
Solubility Soluble in DMSO, THF Limited in non-polar solvents
Storage 2-8°C under inert gas Room temp for stable derivatives

Applications & Industrial Uses

Pharmaceutical Intermediates

Key building block for:

  • Kinase inhibitor development
  • Antiviral drug candidates
  • PET tracer synthesis

Agrochemical Synthesis

  • Novel pesticide formulations
  • Herbicide metabolites

Usage Guidelines

Reaction Optimization

  • Recommended coupling conditions: Pd(PPh3)4 catalyst, 80-100°C
  • Incompatible with strong reducing agents

Case Studies

Case 1: Anticancer Drug Development

Challenge: Low yield in Suzuki-Miyaura coupling

Solution: Optimized solvent system (DME/H2O 4:1)

Result: 82% isolated yield achieved

Client Success Stories

PharmaTech Solutions (Germany)

  • Application: JAK3 inhibitor synthesis
  • Scale: 15kg batch production
  • Outcome: Successful Phase I clinical trials

AgroNova Ltd. (USA)

  • Application: Systemic insecticide development
  • Result: 94% pest mortality rate in field trials

Inquiry & Custom Solutions

Contact our technical team for:

  • Bulk pricing (1kg+ quantities)
  • Custom fluorination services
  • GMP-grade synthesis

Email: info@vivalr.com
Phone: (86) 15866781826

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