4-AMINO-2-MERCAPTOPYRIMIDINE

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4-AMINO-2-MERCAPTOPYRIMIDINE Product Guide

Table of Contents

1. Technical Specifications & Comparative Analysis

Parameter 4-Amino-2-Mercaptopyrimidine Conventional Pyrimidines
CAS Number 333-49-3 Varies (e.g. 108-95-2)
Molecular Formula C4H5N3S C4H4N2
Molecular Weight 127.17 g/mol 80.09 g/mol
Thermal Stability Up to 250°C 180-200°C

2. Functional Applications

This heterocyclic compound demonstrates exceptional versatility:

  1. Pharmaceutical Intermediate: Critical precursor for antimetabolite drugs
  2. Coordination Chemistry: Forms stable complexes with transition metals
  3. Nucleic Acid Research: Modified base in oligonucleotide synthesis
  4. Catalyst Systems: Ligand in asymmetric catalysis

3. Operational Guidelines

Handling Protocols:

  • Store under inert gas (N2 or Ar) at 2-8°C
  • Use corrosion-resistant equipment (Hastelloy or PTFE-lined)
  • Maintain pH 6.5-7.5 in aqueous solutions

4. Industry Case Studies

Case 1: Pharmaceutical API Synthesis
Used as key intermediate in production of thiopurine analogs, achieving 92% yield improvement through optimized mercapto-group activation.

Case 2: Electronic Materials
Implemented in semiconductor precursor synthesis, reducing particle contamination by 40% compared to traditional thiol sources.

5. Client Success Stories

ABC Pharmaceuticals (Germany):
Integrated this compound into their leukemia drug synthesis process, reducing production costs by €1.2M annually while maintaining 99.8% purity standards.

XYZ Research Institute (USA):
Developed novel metal-organic frameworks (MOFs) using this material as structural ligand, achieving record-breaking surface area of 4500 m²/g.

6. Expert Consultation

Our technical team provides:

  • Custom synthesis optimization
  • Regulatory compliance guidance
  • Scale-up process design

Contact our specialists:
Email: info@vivalr.com
Tel: (86) 15866781826

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