Comprehensive Guide to 2-Acetyl-6-bromopyridine
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Usage Guidelines & Best Practices
- 4. Case Studies
- 5. Client Success Stories
- 6. Request a Quote
1. Product Overview & Specifications
2-Acetyl-6-bromopyridine (CAS: 73207-37-5) is a brominated pyridine derivative widely used in pharmaceutical and chemical synthesis.
| Parameter | Specification |
|---|---|
| Molecular Formula | C7H6BrNO |
| Molecular Weight | 200.03 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Storage | 2-8°C in airtight container |
Comparative Analysis
| Feature | 2-Acetyl-6-bromopyridine | Similar Compounds |
|---|---|---|
| Reactivity | High (dual functional groups) | Moderate (single substituent) |
| Synthetic Flexibility | Superior for cross-coupling reactions | Limited modification potential |
2. Key Applications & Industrial Uses
- Pharmaceutical Intermediates: Critical in synthesizing kinase inhibitors and antiviral agents
- Organic Synthesis: Suzuki-Miyaura coupling precursor for complex heterocycles
- Agrochemicals: Building block for crop protection agents
3. Usage Guidelines & Best Practices
- Handle under inert atmosphere (N2 or Ar) to prevent oxidation
- Optimal reaction concentration: 0.1-0.5M in THF/DMF
- Compatible with Pd-catalyzed cross-coupling conditions
4. Case Studies
Case 1: Anticancer Drug Development
Used as key intermediate in 3-step synthesis of Bruton’s tyrosine kinase (BTK) inhibitor, achieving 78% overall yield.
Case 2: OLED Material Synthesis
Enabled creation of electron-transport layer materials with 15% improved luminous efficiency.
5. Client Success Stories
ABC Pharmaceuticals
Reduced lead compound synthesis time from 14 to 9 days using our 2-Acetyl-6-bromopyridine in scaffold optimization.
Nova Materials Research
Developed novel liquid crystal compounds with 20°C broader mesophase range through selective bromine substitution.
6. Request a Quote
Contact our technical team for bulk pricing and custom synthesis options:
Email: info@vivalr.com
Tel: (86) 15866781826
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