2-Acetamido-5-nitropyridine: Technical Guide & User Manual
Table of Contents
1. Product Overview & Specifications
CAS Number: 30074-03-4
Molecular Formula: C7H6N3O3
Purity: ≥98% (HPLC)
Appearance: Yellow crystalline powder
| Parameter | Specification | Competitor A |
|---|---|---|
| Melting Point | 192-195°C | 188-190°C |
| Solubility | DMSO, Ethanol | DMSO only |
2. Key Applications & Industrial Uses
Widely utilized in:
- Pharmaceutical intermediates for kinase inhibitors
- Agrochemical research (herbicide formulations)
- Organic synthesis of heterocyclic compounds
3. Operational Guidelines & Best Practices
Storage: Keep in dark at 2-8°C under inert atmosphere
Handling: Use PPE including nitrile gloves and chemical goggles
Reaction Example:
1. Dissolve 5g in 100ml DMSO at 40°C
2. Add 1.2eq coupling reagent gradually
3. Monitor reaction via TLC (CH2Cl2:MeOH 9:1)
4. Real-World Case Studies
Case 1: Shanghai PharmaTech Co., Ltd.
Application: Synthesis of EGFR inhibitor candidates
Result: Improved yield from 62% to 78% compared to alternative intermediates
Case 2: EuroChem Research
Application: Development of novel fungicides
Result: Achieved 92% purity in final API crystallization
5. Inquiry & Technical Support
For batch-specific COA or custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826
Request free sample or MSDS: Specify required quantity and application purpose.
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