2,5-Difluoropyridine: Comprehensive Product Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 2,5-Difluoropyridine | Similar Compounds |
|---|---|---|
| CAS Number | 84476-99-3 | N/A |
| Molecular Formula | C5H3F2N | C5H4FN (2-Fluoropyridine) |
| Molecular Weight | 115.08 g/mol | 97.09 g/mol |
| Density | 1.274 g/mL | 1.13 g/mL |
| Boiling Point | 113.1–115°C | 92–94°C |
| Melting Point | -33°C | -70°C |
| Flash Point | 22.2–75.2°F | 40°F |
| Purity | ≥98% | ≥95% |
Storage: 2–8°C in sealed containers
Safety: GHS02 (Flammable), GHS07 (Irritant)
2. Key Applications
Pharmaceutical Intermediates
- Synthesis of kinase inhibitors
- Anticancer drug development
- API manufacturing
Agrochemicals
- Herbicide formulations
- Pesticide intermediates
Electronics
- Liquid crystal precursor
- Semiconductor material synthesis
3. Operational Guidelines
Handling Protocols
- Use PPE: Nitrile gloves, chemical goggles
- Operate under fume hood
- Ground equipment to prevent static
Reaction Optimization
- Optimal temperature: 25–40°C
- Compatible solvents: DCM, THF, EtOAc
- Catalyst compatibility: Pd/C, CuI
4. Industry Use Cases
Case A: Antineoplastic Agent Synthesis
Used in 5-step synthesis of EGFR inhibitors with 72% overall yield.
Case B: Crop Protection Chemicals
Key intermediate in next-gen herbicides with 40% improved efficacy.
5. Client Success Stories
PharmaTech Innovations (Shanghai)
- Application: PARP inhibitor development
- Result: Accelerated Phase I trials by 18 months
- Volume: 500 kg/year
AgroSolutions Ltd. (Wuhan)
- Application: Fungicide formulation
- Result: Achieved 99.5% purity in final API
- Volume: 1.2 MT/year
6. Request Quotation
For bulk pricing (25kg+), custom synthesis, or technical support:
Email: info@vivalr.com
Tel: (86) 15866781826
Lead Time: 3–5 business days for samples


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