2-Fluoro-3-hydroxypyridine

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2-Fluoro-3-hydroxypyridine: Comprehensive User Guide

1. Product Overview & Specifications

2-Fluoro-3-hydroxypyridine (CAS: 174669-74-0) is a fluorinated pyridine derivative widely used in pharmaceutical and agrochemical research. Below are its key specifications:

Parameter Value
Molecular Formula C5H4FNO
Molecular Weight 113.09 g/mol
Density 1.3 ± 0.1 g/cm³
Melting Point 126–133°C
Boiling Point 306.7°C at 760 mmHg
Flash Point 139.3°C
PSA 33.12 Ų
LogP 0.93

Note: Variations in melting points (126–133°C) may arise from differences in purity or measurement methods.

2. Key Applications

This compound serves as a versatile intermediate in:

  • Pharmaceuticals: Synthesis of antiviral and anticancer agents.
  • Agrochemicals: Development of herbicides and fungicides.
  • Material Science: Building block for fluorinated polymers or ligands.

3. Usage Scenarios

Scenario 1: Drug Intermediate Synthesis

Used in the multi-step synthesis of kinase inhibitors, where fluorination enhances bioavailability.

Scenario 2: Ligand Preparation

Acts as a chelating agent in metal-catalyzed reactions for asymmetric synthesis.

4. Customer Case Studies

Case Study 1: Shanghai YuBo Bio-Tech

Application: Synthesis of antiviral compounds.
Outcome: Achieved 98% purity in final API batches, reducing production costs by 15%.

Case Study 2: Shanghai YuanYe Biotechnology

Application: Development of fluorinated herbicides.
Outcome: Enhanced herbicidal activity by 30% compared to non-fluorinated analogs.

5. Contact for Inquiries

For pricing, samples, or technical support, contact our team:

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