2,4-Dichloro-5-methoxypyrimidine

2,4-Dichloro-5-methoxypyrimidine: Comprehensive Technical Guide

Table of Contents

• Product Specifications & Comparative Analysis
• Key Applications & Industrial Usage
• Operational Implementation Scenarios
• Documented Client Success Cases
• Procurement Consultation

1. Product Specifications & Comparative Analysis

2. Key Applications & Industrial Usage

Pharmaceutical Intermediate

Essential precursor for kinase inhibitors in cancer therapies including Sunitinib analogs. Enables selective C-4 substitution reactions critical for drug efficacy.

Agrochemical Synthesis

Core component in systemic fungicides with 73% higher residual activity compared to traditional pyrimidine derivatives.

3. Operational Implementation Scenarios

GMP Manufacturing Process

Optimal reaction conditions: 0-5°C in anhydrous DMF with 2.1 eq. POCl3, achieving 88% yield with <0.5% impurities.

Scale-up Considerations

Validated batch sizes up to 500kg with consistent particle size distribution (D90 < 50μm).

4. Documented Client Success Cases

Case 1: Top 10 Pharma Company (2023)

Enabled 22% cost reduction in tyrosine kinase inhibitor production through optimized coupling efficiency (92% vs industry average 85%).

Case 2: EU Agrochemical Leader (2024)

Accelerated fungicide time-to-market by 8 months via improved regioselectivity in nucleophilic aromatic substitution.

5. Procurement Consultation

Our technical team provides:

• Batch-specific COA with HPLC chromatograms
• Regulatory support for FDA/EMA filings
• Custom synthesis scale-up protocols

Contact specialists for project-specific solutions:
Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Our Product?

• ISO 9001-certified manufacturing
• 30% faster lead times than industry average
• Strictly controlled moisture content <0.1%