2-Chloro-5-fluoropyrimidine: Comprehensive Product Guide
Table of Contents
- Product Overview & Specifications
- Applications & Use Cases
- Technical Comparisons
- Operational Guidelines
- Industry Case Studies
- Inquiry & Procurement
1. Product Overview & Specifications
2-Chloro-5-fluoropyrimidine (CAS 374-39-0) is a halogenated pyrimidine derivative widely used in pharmaceutical synthesis and agrochemical R&D.
| Parameter | Specification |
|---|---|
| Molecular Formula | C4H2ClFN2 |
| Molecular Weight | 132.53 g/mol |
| Purity | ≥98% (HPLC) |
| Appearance | White crystalline powder |
| Storage | 2-8°C in dry environment |
2. Key Applications
Primary applications include:
- Intermediate for anticancer drugs (e.g., kinase inhibitors)
- Building block for antiviral medications
- Agrochemical precursor
- Organic synthesis reagent
3. Comparative Analysis
| Compound | Reactivity | Pharma Applications | Stability |
|---|---|---|---|
| 2-Chloro-5-fluoropyrimidine | High | Anticancer/Antiviral | Stable at RT |
| 2-Chloropyrimidine | Moderate | General Synthesis | Air-sensitive |
| 5-Fluorouracil | Low | Oncology | Requires refrigeration |
4. Operational Protocols
Handling Requirements:
- Use PPE: nitrile gloves, safety goggles
- Handle under nitrogen atmosphere
- Solvent compatibility: DMF, THF, dichloromethane
5. Industry Implementations
Case 1: Leading Pharma Company (2023)
Application: Synthesis of third-generation EGFR inhibitors
Outcome: 22% yield improvement vs traditional intermediates
Case 2: European Research Consortium (2024)
Application: Development of broad-spectrum antivirals
Result: Achieved 98.3% purity in final API
6. Procurement Inquiry
Contact our technical team for:
- Custom synthesis options
- Bulk pricing (100kg+ quantities)
- GMP-grade material
Email: info@vivalr.com
Phone: (86) 15866781826
相关产品
Chemical Name: 4-((2-Furylmethyl)thio)-4-methylpentan-2-one
Cas No.: 64835-96-7
Molecular Fomula: C11H16O2S
Molecular Weight: 212.31
Appearance: Colorless to light yellow liquid
Chemical Name: Ammonium Iron(II) Sulfate
Synonyms: Diammonium iron bis(sulphate); iron (ii) ammonium sulfate
CAS No.: 10045-89-3
Molecular Formula: FeH5NO4S
Molecular Weight: 170.95
Chemical Name: 1,5-Diphenylcarbazide
Synonyms: 1,5-Diphenylcarbohydrazide; 2,2’-diphenylcarbazide; Diphenylcartazide; sym-diphenylcarbazide
CAS No.: 140-22-7
Molecular Formula: C13H14N4O
Molecular Weight: 242.28
Common English name: 5-iodo-2,3-dihydropyridazin-3-one
CAS No.: 825633-94-1
Molecular formula: C4H3IN2O
Molecular weight: 221.98
Sample: Available
Chemical Name: 1-Hexadecylamine
Synonyms 1-Aminohexadecane; Hexyldecylamine; n-Certylamine
CAS No.: 143-27-1
Molecular Formula: C16H35N
Molecular Weight: 241.46
Appearance: White Crystal
Chemical Name: D-PANTOTHENIC ACID
CAS No.: 79-83-4
Molecular Formula: C9H17NO5
Molecular Weight: 219.24
Appearance: Colorless or Light Yellow Oily Liquid
Chemical Name: Choline salicylate
CAS No.: 2016-36-6
Molecular Formula: C12H19NO4
Molecular Weight: 241.28
Appearance: Red-Brown Crystal
Chemical Name: Zinc citrate
Synonyms: Zinc citrate trihydrate
CAS No.: 546-46-3
Molecular Formula: C6H8O7Zn
Molecular Weight: 257.5
Appearance: White powder
Chemical Name: D-Phenothrin
CAS No.: 26046-85-5
Molecular Formula: C23H26O3
Molecular Weight: 350.45
Appearance: Oil
Chemical Name: 3-Hydroxybutyric acid
CAS No.: 625-71-8
Molecular Formula: C4H8O3
Molecular Weight: 104.1
Appearance: White powder
Chemical Name: 3-Hydroxybutyric acid
CAS No.: 625-71-8
Molecular Formula: C4H8O3
Molecular Weight: 104.1
Appearance: White powder
Chemical Name: DL-4-Chlorophenylglycine
Cas No.: 6212-33-5
Molecular Fomula: C8H8ClNO2
Molecular Weight: 185.61
评论
目前还没有评论。