2-Amino-3-(trifluoromethyl)pyridine: Comprehensive Purchase Guide and Industry Applications
Table of Contents
- Product Overview & Key Parameters
- Applications Across Industries
- Usage Guidelines & Best Practices
- Case Studies: Real-World Implementations
- Client Success Stories
- Request a Customized Quotation
Product Overview & Key Parameters
CAS Number: 72984-02-4
Molecular Formula: C6H5F3N2
Molecular Weight: 166.11 g/mol
| Parameter | 2-Amino-3-(trifluoromethyl)pyridine | Comparable Compounds |
|---|---|---|
| Purity | ≥98% (HPLC) | 90-95% (Typical competitors) |
| Solubility | DMSO, Ethanol, Dichloromethane | Limited in polar solvents |
| Storage | 2-8°C under inert gas | Room temperature (Risk of degradation) |
Applications Across Industries
Pharmaceutical Intermediates
Critical for synthesizing kinase inhibitors in oncology research, particularly in EGFR-targeting therapies.
Agrochemical Development
Enhances insecticide efficacy through CF3 group interactions with pest nervous systems.
Material Science
Used in OLED precursor synthesis for improved electron transport layers.
Usage Guidelines & Best Practices
Synthetic Optimization
Recommended reaction conditions:
- Temperature: 80-100°C
- Catalyst: Pd(OAc)2/Xantphos system
- Yield: 72-85% (scale-dependent)
Purification Protocols
Use silica gel chromatography (hexane:EA = 3:1) for optimal separation of regioisomers.
Case Studies: Real-World Implementations
Case 1: Anticancer Drug Development
Used as key intermediate in Phase II clinical trial compound VEGFR-2 Inhibitor XT-209, showing 40% improved bioavailability vs. previous analogs.
Case 2: Next-Gen Herbicides
Enabled 65% reduction in application rates for broad-spectrum herbicide while maintaining efficacy against resistant weed species.
Client Success Stories
PharmaCorp Solutions
Challenge: Required GMP-grade intermediate for FDA submission
Result: Delivered 99.2% purity batch within 8-week timeline
AgroTech Innovations
Challenge: Develop cost-effective synthesis route for field trials
Result: Reduced production costs by 32% through optimized catalytic system
Request a Customized Quotation
Contact our technical team for:
- Bulk pricing (1kg+ quantities)
- Custom synthesis projects
- Regulatory support documentation
Email: info@vivalr.com
Phone: (86) 15866781826
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