5-FLUORO-2-METHOXYNICOTINALDEHYDE

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5-Fluoro-2-methoxynicotinaldehyde: Comprehensive User Guide

1. Product Overview & Specifications

5-Fluoro-2-methoxynicotinaldehyde (CAS 1209408-12-3) is a fluorinated nicotinaldehyde derivative with the molecular formula C8H6FNO2 and a molecular weight of 167.14 g/mol. This heterocyclic compound is widely used as a key intermediate in pharmaceuticals and agrochemicals.

Key Parameters & Comparison

Parameter 5-Fluoro-2-methoxynicotinaldehyde 2-Methoxynicotinaldehyde
Purity ≥98% (HPLC) ≥95%
Melting Point 72-75°C 68-70°C
Fluorine Content 11.37% 0%

*Fluorination enhances metabolic stability in API synthesis.

2. Applications & Use Cases

Pharmaceutical Intermediates

Used in synthesizing kinase inhibitors and antiviral agents. The fluorine atom improves bioavailability and target binding affinity.

Agrochemical Development

Critical for creating herbicidal compounds with enhanced leaf permeability due to its lipophilic properties.

Chemical Research

Acts as a building block for fluorescent probes in bioimaging studies.

3. Industry Case Studies

Case 1: Antiviral Drug Development

Client: Tier-1 European Pharma Company
Application: Synthesis of RNA polymerase inhibitor intermediates
Result: Achieved 92% yield in palladium-catalyzed coupling reactions.

Case 2: Herbicide Formulation

Client: Agrochemical Manufacturer (USA)
Application: Development of systemic herbicides
Result: 40% improvement in rainfastness compared to non-fluorinated analogs.

Case 3: OLED Material Research

Client: Asian Electronics Conglomerate
Application: Electron-transport layer components
Result: Enhanced device lifetime by 15% at 1000 cd/m² luminance.

4. Technical Support & Inquiry

Request custom synthesis or bulk pricing:

info@vivalr.com
(86) 15866781826

MSDS and COA available upon request. Global shipping with cold-chain support.

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