6-(TRIFLUOROMETHYL)URACIL

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6-(Trifluoromethyl)Uracil: Product Overview & Specifications

Basic Chemical Properties

Parameter Specification Comparison with Standard Uracil
CAS Number 34468-01-0 Unique fluorine substitution pattern
Molecular Formula C5H3F3N2O2 Increased molecular weight (180.09 g/mol)
Purity >98% (HPLC) Enhanced stability vs. non-fluorinated analogs
Solubility DMSO: 50 mg/mL, Water: <1 mg/mL Improved lipophilicity for drug delivery
Storage 2-8°C in inert atmosphere Longer shelf life (3 years) vs. 2 years for regular uracil

Key Differentiators

  • Superior metabolic stability compared to non-fluorinated uracil derivatives
  • Enhanced electron-withdrawing properties for catalytic applications
  • Reduced decomposition rate under physiological conditions

Key Industrial Applications

Pharmaceutical Intermediates

  • Critical component in antiviral drug synthesis (e.g., HIV protease inhibitors)
  • Building block for fluorinated nucleoside analogs in oncology research
  • Improves drug bioavailability through fluorine-mediated membrane permeability

Agrochemical Formulations

  • Active ingredient in next-generation fungicides (FRAC Code: 29)
  • UV-stable formulation component for field applications
  • Resistance management agent in combination herbicides

Electronics Manufacturing

  • Precursor for fluorine-doped carbon nanomaterials
  • Etching agent in semiconductor lithography processes
  • Dielectric layer modifier in flexible displays

Industry Success Stories

Case Study 1: Antiviral Drug Development

Client: Top 10 Global Pharma Company
Challenge: Improve metabolic stability of lead compound
Solution: Incorporated 6-(Trifluoromethyl)Uracil in molecular scaffold
Result: 73% increase in plasma half-life (NHP model)

Case Study 2: High-Performance Fungicide

Client: European Agrochemical Manufacturer
Challenge: Develop rainfast formulation with systemic action
Solution: 0.5% w/w 6-(Trifluoromethyl)Uracil in tank mix
Result: 98% Botrytis control 14 days post-application (EU field trials)

Safety & Handling Protocols

Aspect Requirement
PPE Nitrile gloves, chemical goggles, Type II respirator
Spill Management Neutralize with 5% sodium bicarbonate solution
Waste Disposal Incinerate at 1200°C+ with alkaline scrubber
First Aid Immediate eye irrigation (15 mins minimum)

Request Product Information

For technical specifications, MSDS, or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Our Product?

  • Batch-to-batch consistency (RSD <1.5%)
  • Custom synthesis capabilities (mg to kg scale)
  • Regulatory support for FDA/EPA submissions
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