2-Amino-6-bromopyridine

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Comprehensive Product Guide for 2-Amino-6-bromopyridine

Table of Contents

1. Product Overview & Specifications

Parameter Value
CAS Number 19798-81-3
Molecular Formula C5H5BrN2
Molecular Weight 173.01 g/mol
Appearance White to off-white crystalline powder
Purity (HPLC) ≥98%
Melting Point 89-92°C
Storage Conditions 2-8°C in dark, dry environment

Comparative Analysis

Compound Reactivity Stability Price/kg
2-Amino-6-bromopyridine High Excellent $420-480
2-Amino-5-bromopyridine Moderate Good $380-420
2-Amino-4-bromopyridine Low Fair $350-390

2. Key Applications & Industrial Uses

Pharmaceutical Intermediates

Essential for synthesizing kinase inhibitors (e.g., EGFR inhibitors) and antiviral agents. Enables precise bromine substitution in heterocyclic systems.

Organic Synthesis

Facilitates cross-coupling reactions (Suzuki, Buchwald-Hartwig) for functionalized pyridine derivatives in agrochemicals and specialty chemicals.

Material Science

Building block for OLED electron-transport materials and coordination compounds with transition metals.

3. Handling & Safety Guidelines

Aspect Requirement
Personal Protection Nitrile gloves, chemical goggles, lab coat
Ventilation Fume hood required for bulk handling
Incompatibilities Strong oxidizers, acids, moisture
First Aid Measures Flush eyes with water for 15min if contacted

4. Performance Comparison

Superior bromine activation compared to chloro-analogs enables lower catalyst loading (15-20% reduction) in coupling reactions.

5. Client Case Studies

Case 1: Anticancer Drug Development

Client: Top 10 Global Pharma Company
Application: BTK inhibitor intermediate synthesis
Result: Achieved 92% yield in Buchwald-Hartwig amination

Case 2: OLED Material Production

Client: Asian Electronic Materials Manufacturer
Application: Electron-transport layer precursor
Result: Enhanced device lifetime by 30% (vs. previous formulation)

Case 3: Academic Research

Client: European University Chemistry Department
Application: Palladium complex synthesis for catalysis studies
Result: Enabled 5 published papers in ACS journals

6. Request Customized Solution

Contact our technical team for batch-specific COA or custom synthesis services:

  • Email: info@vivalr.com
  • Phone: (86) 15866781826

Why Choose Us?
✓ Pharmaceutical-grade quality
✓ Flexible packaging (1g-25kg)
✓ ISO 9001 certified production

Frequently Asked Questions

Question Answer
Maximum batch purity? Up to 99.7% (HPLC)
Lead time for 10kg? 2-3 weeks
Custom bromination services? Available (submit inquiry)
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