Parameter | 2-Amino-5-nitropyridine | Similar Compounds |
---|---|---|
CAS Number | 4214-76-6 | Varies by derivative |
Molecular Formula | C5H5N3O2 | Different N/O ratios |
Purity Grade | ≥98% (HPLC) | Typically 95-99% |
Thermal Stability | Stable ≤200°C | Varies widely |
Pharmaceutical Intermediate: Critical precursor for antitumor agents and kinase inhibitors.
Agrochemical Synthesis: Core component in next-generation herbicides and fungicides.
Coordination Chemistry: Effective ligand for transition metal catalysts in cross-coupling reactions.
Handling: Use nitrogen atmosphere for moisture-sensitive reactions
Solvent Compatibility: Optimal performance in DMF/DMSO systems (0.1-0.5M concentrations)
Safety: PPE requirements: Nitrile gloves, vapor respirator for powder processing
Drug Discovery: Key building block in EGFR inhibitor development (83% yield improvement vs. analogs)
Crop Protection: Enables synthesis of systemic herbicides with 40% faster activation
Material Science: Facilitates creation of conductive coordination polymers (σ = 10-3 S/cm)
Case 1: Top 10 Pharma Company - Accelerated oncology pipeline development by 6 months through improved intermediate synthesis
Case 2: EU Agrochemical Leader - Achieved 22% cost reduction in herbicide production via optimized nitropyridine integration
Case 3: University Research Consortium - Developed novel MOF materials with enhanced catalytic properties
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