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5-Methylpyridine-3-boronic Acid: Technical Guide & Applications
Table of Contents
- Product Overview & Specifications
- Key Applications & Industrial Uses
- Performance Comparison with Similar Boronic Acids
- Synthesis & Handling Guidelines
- Case Studies: Pharmaceutical & Material Science Applications
- Inquiry & Technical Support
1. Product Overview & Specifications
| Parameter | 5-Methylpyridine-3-boronic Acid | Pyridine-3-boronic Acid | 4-Methylpyridine-2-boronic Acid |
|---|---|---|---|
| CAS Number | 1197196-64-3 | 150360-46-6 | 1072940-48-0 |
| Molecular Formula | C6H8BNO2 | C5H6BNO2 | C6H8BNO2 |
| Purity (HPLC) | ≥98% | ≥95% | ≥97% |
| Storage Temperature | 2-8°C (desiccated) | Ambient | 2-8°C |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediate: Critical component in Suzuki-Miyaura cross-couplings for:
- Kinase inhibitor development (EGFR, ALK targets)
- Anticancer drug candidates (Phase II/III clinical trials)
- Antiviral compound synthesis
Material Science:
- OLED precursor synthesis (electron-transport layers)
- Coordination polymers for gas storage
- MOF (Metal-Organic Framework) construction
5. Verified Application Cases
Case 1: Oncology Drug Development
Client: Top 10 Global Pharma Company (Confidential)
- Application: Third-generation EGFR inhibitor synthesis
- Scale: 200kg batch production
- Result: 92% coupling efficiency in flow chemistry system
Case 2: OLED Material Production
Client: Leading Korean Display Manufacturer
- Application: Electron transport layer precursor
- Spec Requirement: ≤50ppm metal impurities
- Outcome: Achieved 99.5% purity with 28ppm residual Pd
6. Technical Inquiry & Ordering
Contact our boron chemistry specialists:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Request:
- Custom synthesis scaling (100g to 500kg)
- GMP-grade material options
- Regulatory documentation support
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