Comprehensive Guide to 2,6-Dibromopyridine-4-carboxylic Acid
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications
- 3. Usage Scenarios
- 4. Industry Case Studies
- 5. Technical Comparison
- 6. Contact for Custom Solutions
1. Product Overview & Specifications
| Parameter | 2,6-Dibromopyridine-4-carboxylic Acid |
|---|---|
| CAS Number | 102668-27-7 |
| Molecular Formula | C7H3Br2NO2 |
| Molecular Weight | 315.92 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥98% |
| Storage Conditions | 2-8°C in airtight container |
2. Key Applications
- Pharmaceutical intermediates for kinase inhibitors
- Cross-coupling reactions in organic synthesis
- Agrochemical precursor development
- Coordination chemistry building block
- Functional material synthesis
3. Usage Scenarios
3.1 Medicinal Chemistry Applications
Used as key intermediate in JAK2 inhibitors synthesis through Buchwald-Hartwig amination reactions. Enables precise bromine substitution patterns for targeted drug design.
3.2 Catalytic Systems
Facilitates palladium-catalyzed cross-couplings in API manufacturing. Demonstrates exceptional stability under Suzuki-Miyaura reaction conditions.
4. Industry Case Studies
4.1 Pharmaceutical Development (ABC Therapeutics)
Challenge: Required high-purity brominated pyridine derivative for oncology drug candidate
Solution: Custom synthesis with >99.5% purity
Outcome: Accelerated IND filing timeline by 3 months
4.2 Agricultural Chemistry (GreenCrop Solutions)
Challenge: Needed stable precursor for novel fungicide
Solution: Optimized bromination process for batch consistency
Outcome: Achieved 92% yield in final coupling reaction
5. Technical Comparison
| Feature | 2,6-Dibromo | 2-Bromo Analog | Tribromo Derivative |
|---|---|---|---|
| Reactivity | High | Moderate | Unstable |
| Solubility | DMSO >50mg/ml | DMSO >100mg/ml | <10mg/ml |
6. Contact for Custom Solutions
For bulk orders or specialized derivatives:
Email: info@vivalr.com
Phone: (86) 15866781826
Request custom synthesis parameters:
– Scale requirements (mg to kg scale)
– Purity specifications
– Packaging preferences
– Regulatory documentation needs


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