1. Product Overview & Specifications

2,4-Dichloro-5-nitropyrimidine (CAS 6625-76-1) is a versatile pyrimidine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters:

*Comparison with 2,4,6-Trichloropyrimidine (A) and 5-Nitro-2,4-pyrimidinediol (B)

2. Key Applications

Pharmaceutical Intermediates

Used in synthesis of:

• Anticancer agents (EGFR inhibitors)
• Antiviral drugs (HCV protease inhibitors)

Agrochemical Production

Critical component for:

• Herbicide intermediates
• Insect growth regulators

3. Usage Scenarios

Scenario 1: Anticancer Drug Synthesis

Process: Nucleophilic substitution at C-4 position → Nitro group reduction → Cyclization
Yield: 82-87% (vs. 75% with alternative intermediates)

Scenario 2: Herbicide Formulation

Application: Precursor for sulfonylurea herbicides
Advantage: 20% faster reaction kinetics vs. chloro-nitro analogs

4. Client Case Studies

Case 1: ABC Pharma (Germany)

Challenge: Improve lapatinib intermediate synthesis efficiency
Solution: Implemented 2,4-Dichloro-5-nitropyrimidine in Suzuki coupling
Result: 18% cost reduction per kg API

Case 2: GreenAgro Solutions (USA)

Challenge: Develop temperature-stable herbicide
Solution: Used as core structure in new sulfonylurea compound
Result: 40% longer field stability vs. previous formula

5. Contact for Custom Solutions

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• Custom synthesis protocols
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