2-Fluoro-4-methyl-5-nitropyridine: Technical Guide & Industry Applications
Contents
- Product Overview
- Specification Comparison
- Key Applications
- Usage Guidelines
- Industry Case Studies
- Contact for Custom Solutions
Product Overview
| Parameter | Specification |
|---|---|
| CAS Number | 1072-14-0 |
| Molecular Formula | C6H5FN2O2 |
| Purity | ≥98% (HPLC) |
| Appearance | Yellow crystalline powder |
| Storage Conditions | 2-8°C in airtight container |
Comparative Analysis
| Derivative | Fluorine Position | Reactivity | Typical Yield |
|---|---|---|---|
| 2-Fluoro-4-methyl-5-nitropyridine | Ortho | High | 85-92% |
| 3-Fluoro-5-nitropyridine | Meta | Moderate | 72-78% |
Industrial Applications
Pharmaceutical Intermediates
Critical component in synthesis of:
- Kinase inhibitor precursors
- Anticancer drug candidates
- Antiviral compound backbones
Agrochemical Development
Essential for creating:
- Next-gen pesticide formulations
- Herbicide metabolites
- Fungicide active ingredients
Operational Protocols
Laboratory Handling
- Use dry nitrogen atmosphere for sensitive reactions
- Maintain reaction temperature below -10°C for nitro group stability
- Employ Pd/C catalyst for hydrogenation steps
Industrial Scale Processing
- Implement continuous flow reactors for nitration steps
- Monitor exothermic reactions with RTD sensors
- Utilze cryogenic distillation for purification
Client Success Stories
Case 1: Oncology Research Institute
- Challenge: Low yield in kinase inhibitor synthesis
- Solution: Optimized fluoropyridine coupling conditions
- Result: 40% yield improvement
Case 2: Agrochemical Manufacturer
- Challenge: Unstable intermediate in pesticide production
- Solution: Modified nitro group protection strategy
- Result: 99.5% intermediate stability achieved
Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100kg+ quantities)
- Custom fluorination services
- GMP-grade production options
Email: info@vivalr.com
Phone: (86) 15866781826


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