3-Amino-6-Chloro-4-Picoline: Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
CAS No.: 66909-38-4
IUPAC Name: 3-Amino-6-chloro-4-methylpyridine
Synonyms: 2-Chloro-5-amino-4-methylpyridine; 6-Chloro-4-methylpyridin-3-amine
Physical Properties
| Property | Value |
|---|---|
| Appearance | Bordeaux to brown crystalline powder |
| Melting Point | 69–73°C |
| Boiling Point | 309.7°C at 760 mmHg |
| Density | 1.26 g/cm³ |
| Refractive Index | 1.592 |
| Flash Point | 141.1°C |
2. Key Applications
- Pharmaceutical Intermediates: Used in synthesizing active pharmaceutical ingredients (APIs) for antiviral and anticancer drugs.
- Agrochemicals: Key component in pesticide formulations targeting crop pathogens.
- Material Science: Building block for advanced polymers and coordination complexes.
- Analytical Chemistry: Chelating agent for spectrophotometric determination of transition metals.
3. Usage Guidelines
Storage: Store in a cool, dry place (2–8°C) under inert atmosphere. Shelf life: 24 months.
Handling: Use PPE (gloves, goggles) in well-ventilated areas. Avoid contact with strong oxidizers.
Solubility: Soluble in ethanol, DMSO, and dichloromethane; sparingly soluble in water.
4. Industry Case Studies
Case 1: Antiviral Drug Development
A European pharmaceutical company utilized this compound as a critical intermediate in synthesizing a novel RNA polymerase inhibitor, achieving 98.5% purity in final API batches.
Case 2: Polymer Catalyst Synthesis
A materials research institute developed a nickel-based coordination catalyst using 3-amino-6-chloro-4-picoline, enhancing catalytic efficiency by 40% in cross-coupling reactions.
5. Client Success Stories
Client A: Top-10 Global Pharma Company
Integrated this compound into their HCV drug pipeline, reducing synthesis steps from 7 to 4 while maintaining >99% enantiomeric purity.
Client B: Specialty Chemicals Manufacturer
Scaled production of corrosion-resistant coatings using our product, achieving 200-ton/year capacity with 99.2% batch consistency.
6. Request a Quote
Contact our technical team for pricing, bulk orders, or custom synthesis:
| info@vivalr.com | |
| Phone | (86) 15866781826 |
| Lead Time | 7–14 days (standard orders) |


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