6-Chloropyridazine-3-carboxylic acid

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Comprehensive Guide to 6-Chloropyridazine-3-carboxylic Acid

Table of Contents

1. Product Overview & Specifications

Parameter Specification
Chemical Name 6-Chloropyridazine-3-carboxylic acid
CAS Number 958647-87-3
Molecular Formula C₅H₃ClN₂O₂
Molecular Weight 174.55 g/mol
Appearance White to off-white crystalline powder
Purity (HPLC) ≥98%
Solubility Soluble in DMSO, slightly soluble in methanol
Storage Conditions 2-8°C in dry, dark environment

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate

Critical building block for synthesizing kinase inhibitors and antiviral agents. Particularly effective in creating pyridazine-based drug candidates targeting cancer therapies.

Agrochemical Development

Core component in next-generation herbicides and fungicides, demonstrating enhanced bioactivity against resistant plant pathogens.

Material Science Applications

Used as coordination ligand in metal-organic frameworks (MOFs) for catalytic systems and gas storage solutions.

3. Operational Guidelines & Safety Protocols

Handling Requirement Protocol Detail
Personal Protection Nitrile gloves, chemical goggles, lab coat
Ventilation Use in fume hood with ≥100 fpm airflow
Spill Management Absorb with inert material, neutralize with 5% sodium bicarbonate
Thermal Stability Decomposes at 245°C – avoid prolonged heat exposure

4. Case Studies: Real-World Implementations

Case 1: Antiviral Drug Development

Client: European Pharma Research Consortium
Challenge: Required high-purity intermediate for Phase II clinical trial material
Solution: Supplied 25kg GMP-grade material with 99.7% purity
Outcome: Accelerated production timeline by 40%, achieved 92% yield in final coupling reaction

Case 2: Agricultural Formulation

Client: Asia-Pacific Agrochemical Manufacturer
Challenge: Needed cost-effective synthesis route for novel fungicide
Solution: Customized technical-grade material with optimized particle size distribution
Outcome: Reduced production costs by 28% while maintaining 98% bioefficacy

5. Competitive Parameter Analysis

Feature Standard Grade Premium Grade GMP Grade
Purity 98% 99% 99.5%+
Heavy Metals <10 ppm <5 ppm <2 ppm
Residual Solvents Meets ICH Q3C Class 2 solvents <300 ppm Class 3 only
Batch Consistency ±2% ±1% ±0.5%
Lead Time 2-3 weeks 4-5 weeks 8-10 weeks

6. Consultation & Procurement Support

Our technical team provides:

  • Custom synthesis protocols
  • Regulatory documentation support
  • Scale-up assistance from lab to production

Contact our specialists for tailored solutions:
Email: info@vivalr.com
Phone: (86) 15866781826

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