2-Amino-5-Bromo-4-Hydroxy-6-Methylpyrimidine: Technical Overview
Table of Contents
1. Basic Information & Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Amino-5-bromo-4-hydroxy-6-methylpyrimidine |
| CAS Number | 6307-35-3 |
| Molecular Formula | C5H6BrN3O |
| Molecular Weight | 204.02 g/mol |
| Appearance | White to off-white crystalline powder |
| Melting Point | 244-246°C |
| LogP | 1.42 |
2. Key Applications
This brominated pyrimidine derivative serves as a critical intermediate in:
- Pharmaceutical synthesis (kinase inhibitor precursors)
- Agrochemical research (herbicide development)
- Coordination chemistry (ligand for metal complexes)
- Biochemical studies (enzyme substrate analogs)
3. Safety Considerations
| Hazard Code | Risk Statement |
|---|---|
| H302 | Harmful if swallowed |
| H318 | Causes serious eye damage |
Recommended PPE: Chemical goggles, nitrile gloves, and lab coat. Store in cool, dry conditions (2-8°C) under inert atmosphere.
4. Industry Applications
Case Study 1: Pharmaceutical Development
Shanghai Medichem utilized this compound as a key intermediate in developing selective kinase inhibitors, achieving 78% yield improvement in final API synthesis.
Case Study 2: Agricultural Research
Jiangsu Agrosolutions incorporated the material in novel herbicide formulations, demonstrating 92% weed suppression in field trials.
5. Contact for Technical Support
Email: info@vivalr.com
Tel: (86) 15866781826
Office Hours: Mon-Fri 08:30-17:30 CST
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