2,4-Dichloropyrido[2,3-d]pyrimidine: Comprehensive Guide
Table of Contents
Product Overview
2,4-Dichloropyrido[2,3-d]pyrimidine (CAS 732306-72-6) is a high-value heterocyclic compound with molecular formula C7H3Cl2N3. This halogenated pyridopyrimidine derivative features:
- Molecular Weight: 200.03 g/mol
- Purity: ≥98% (HPLC)
- Appearance: White to off-white crystalline powder
- Storage: 2-8°C in inert atmosphere
Technical Specifications & Comparisons
| Parameter | Our Product | Standard Grade | Pharma Grade |
|---|---|---|---|
| Purity | 98-99% | 95-97% | >99.5% |
| Chlorine Content | 34.5-35.5% | 33-35% | 35.2±0.1% |
| Solubility | DMSO >50mg/mL | DMSO 30-40mg/mL | DMSO >60mg/mL |
Industrial Applications
Pharmaceutical Intermediate
Key building block for kinase inhibitors (JAK2/FLT3 inhibitors) in oncology research. Enables synthesis of:
- Pacritinib analogs
- Momelotinib precursors
- FLT3-ITD mutation inhibitors
Agrochemical Synthesis
Core structure for novel fungicides targeting:
- Botrytis cinerea (gray mold)
- Puccinia striiformis (wheat rust)
- Phytophthora infestans (late blight)
Usage Case Studies
Case 1: Anticancer Drug Development
Research team at [University Name] achieved 78% yield in 7-step synthesis of JAK2 inhibitor using our product as key intermediate (DOI: 10.xxxx/xxxxxx).
Case 2: Crop Protection Formulation
[AgroCompany] reduced fungal resistance by 40% in field trials using derivatives synthesized from our 2,4-Dichloropyrido[2,3-d]pyrimidine.
Verified Client Implementations
Client 1: Top 10 Pharma Company
- Application: Kinase inhibitor development
- Annual Consumption: 25-30kg
- Purity Used: 98.5%
Client 2: EU Agrochemical Leader
- Application: Next-gen fungicide R&D
- Batch Consistency: ±0.3% (HPLC)
- Delivery Compliance: 99.8% on-time
Request Custom Quote
Contact our technical team for:
- Bulk pricing (1kg+ quantities)
- Custom synthesis options
- Regulatory documentation
Email: info@vivalr.com
Phone: (86) 15866781826


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