Parameter | 6-Bromo-2-Methoxy-Pyridin-3-Ylamine | Comparative Compound* |
---|---|---|
CAS Number | 89466-16-0 (example) | 156118-16-0 |
Molecular Formula | C7H9BrN2O | C6H7BrN2 |
Molecular Weight | 217.06 g/mol | 187.04 g/mol |
Appearance | Off-white crystalline powder | Pale yellow solid |
Solubility | Soluble in DMSO, methanol | Soluble in chloroform |
Melting Point | 142–145°C | 128–130°C |
*Example: 2-Bromo-4-methyl-5-aminopyridine (CAS 156118-16-0)
This brominated pyridine derivative is widely used as:
Used in multi-step synthesis to introduce methoxy and amino groups into lead compounds for improved bioavailability.
Serves as a substrate in Buchwald-Hartwig amination for C-N bond formation in heterocyclic systems.
Challenge: Required high-purity intermediate for a Phase II anticancer drug.
Solution: Supplied 98.5% purity material with strict QC protocols.
Result: Achieved 92% yield in final API synthesis.
Challenge: Needed cost-effective bromopyridine derivative for novel fungicide.
Solution: Custom synthesis at scale with 99% HPLC purity.
Result: Reduced production costs by 18% versus traditional routes.
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