2-Amino-6-chloro-4-pyrimidinol

2-Amino-6-chloro-4-pyrimidinol is a heterocyclic organic compound with the molecular formula C₄H₄ClN₃O and a molecular weight of 145.56 g/mol. It is also known by its CAS registry number 1194-21-4. This compound features a pyrimidine backbone substituted with amino (-NH₂), chloro (-Cl), and hydroxyl (-OH) groups at positions 2, 6, and 4, respectively.

Key Physicochemical Properties:

• Appearance: Light yellow crystalline solid (specific data on color and form may vary depending on purity).
• Melting Point: Decomposes at approximately 252°C.
• LogP: 0.93 (indicating moderate lipophilicity).
• Water Solubility: Limited solubility in water (exact values not reported).

Toxicological Data:

• Acute Toxicity (LD₅₀): 180 mg/kg (intravenous administration in mice).
• Hazard Classification: Harmful if swallowed (H302) and toxic to aquatic life with long-lasting effects (H411).

Applications:

This compound serves as a versatile intermediate in organic synthesis, particularly in the development of:

• Pharmaceuticals: Used in the synthesis of antiviral agents and enzyme inhibitors due to its pyrimidine core structure.
• Agrochemicals: Acts as a precursor for herbicides and plant growth regulators.
• Research Chemicals: Employed in biochemical studies targeting nucleotide analogs and enzyme-substrate interactions.

Commercial Availability:

Major suppliers include:

• Hubei Bide Chemical Co., Ltd. (China)
• Hubei Jusheng Technology Co., Ltd. (China)
• Shanghai Civi Chemical Technology Co., Ltd. (China)

Safety Precautions:

• Use personal protective equipment (gloves, goggles, lab coat) when handling.
• Avoid inhalation of dust and direct contact with skin/eyes.
• Store in a cool, dry place away from incompatible materials.
• Follow proper waste disposal protocols to prevent environmental contamination.

For technical specifications, bulk pricing, or customized synthesis requirements, please contact our technical team at info@vivalr.com or call (86) 15866781826.