2,6-Dichloroisonicotinonitrile

Comprehensive Guide to 2,6-Dichloroisonicotinonitrile

Table of Contents

• Product Overview
• Specifications & Comparative Analysis
• Key Applications
• Usage Case Studies
• Client Case Studies
• Request a Quote

1. Product Overview

2,6-Dichloroisonicotinonitrile (CAS 89976-53-8) is a halogenated pyridine derivative widely used as a critical intermediate in pharmaceutical and agrochemical synthesis. Its molecular formula is C₆H₂Cl₂N₂, with a molecular weight of 174.00 g/mol. The compound typically appears as a white to off-white crystalline powder with ≥98% purity.

2. Specifications & Comparative Analysis

3. Key Applications

Pharmaceutical Applications

Used as a key building block in the synthesis of:

• Kinase inhibitors (e.g., EGFR inhibitors)
• Anticancer agents
• Antiviral compounds

Agrochemical Applications

• Intermediate for neonicotinoid insecticides
• Herbicide precursors

4. Usage Case Studies

Case 1: Synthesis of Anticancer Compound XYZ-123

Reaction Steps:

1. Mixing with 2-aminopyridine in DMF (1:1.2 molar ratio)
2. Heating at 80°C for 6 hours under N₂
3. Catalytic hydrogenation using Pd/C

Yield Improvement: 72% → 88% after process optimization

5. Client Case Studies

Client 1: Top-10 Pharma Company (EU)

Application: Production of Investigational New Drug ABC-2024
Volume: 850 kg/year
Results: Reduced synthesis steps from 5 to 3, saving $2.8M/year

Client 2: Agrochemical Manufacturer (USA)

Application: Next-gen insecticide formulation
Technical Support: Custom particle size optimization (D90 < 50μm)
Outcome: 22% improvement in field efficacy

6. Request a Quote

Contact our technical team for customized solutions:

• Email: info@vivalr.com
• Tel: (86) 15866781826

Why Choose Us?

• Batch-to-batch consistency: RSD <1%
• Custom synthesis capabilities
• GMP-compliant production facilities