4-(4-Aminobenzyl)piperazine-1-carboxylic acid tert-butyl ester

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4-(4-Aminobenzyl)piperazine-1-carboxylic acid tert-butyl ester: Comprehensive User Guide

1. Product Overview & Comparative Analysis

Key Specifications

Parameter Specification
CAS Number 147083-93-0
Molecular Formula C17H25N3O2
Molecular Weight 303.41 g/mol
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder

Competitive Benchmarking

Feature Our Product Generic Alternatives
Boc Protection Stability Stable up to 12 months at 2-8°C 6-8 months typical
Aminobenzyl Reactivity Controlled orientation for selective coupling Randomized coupling common
Pharma-Grade Certification ISO 9001:2015 compliant Limited documentation

2. Detailed Applications

Pharmaceutical Intermediates

Enables precise synthesis of:

  • Kinase inhibitor scaffolds
  • GPCR-targeted compounds
  • Anticancer drug candidates

Chemical Biology Probes

  • Amine-reactive conjugation sites
  • Controlled release via Boc deprotection

3. Usage Scenarios & Case Studies

Case Study A: Antiviral Drug Development

Challenge: Achieve >95% coupling efficiency in nucleoside analog synthesis
Solution: Utilized aminobenzyl group for directed ortho-metalation
Outcome: 97.3% yield with 99.1% purity

Case Study B: PET Tracer Synthesis

Challenge: Radiolabeling efficiency below 80%
Solution: Boc protection prevented amine interference
Outcome: 89% radiochemical yield achieved

4. Client Success Stories

Global Pharma Leader (Top 10 Innovator)

Application: JAK2 inhibitor scale-up
Results: Reduced synthesis steps from 7 to 4
Testimonial: “Critical for our Phase III candidate manufacturing”

Biotech Startup (CNS Focus)

Application: Dopamine D3 receptor modulator
Results: 40% cost reduction in lead optimization
Testimonial: “Accelerated our IND submission timeline”

5. Request Customized Solutions

Contact our technical team for:

  • Bulk pricing (1kg+ quantities)
  • Custom purity profiles (up to 99.9%)
  • Regulatory support (DMF filings)

Email: info@vivalr.com
Phone: (86) 15866781826

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