5-(Hydroxymethyl)dihydrofuran-2(3H)-one (CAS 10374-51-3) Comprehensive Guide
Table of Contents
- Product Overview & Specifications
- Applications & Use Cases
- Comparative Analysis with Alternatives
- Industry Case Studies
- Client Success Stories
- Inquiry & Technical Support
1. Product Overview & Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 5-(Hydroxymethyl)dihydrofuran-2(3H)-one |
| CAS Number | 10374-51-3 |
| Molecular Formula | C5H8O3 |
| Molecular Weight | 116.12 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Melting Point | 78-82°C |
| Solubility | Soluble in DMSO, methanol; sparingly soluble in water |
| Storage | 2-8°C in airtight container |
2. Applications & Use Cases
Pharmaceutical Intermediates
Key building block in antiviral drug synthesis (e.g., Tenofovir precursors).
Organic Synthesis
Used in asymmetric catalysis for chiral molecule production.
Research Applications
Critical component in nucleotide analog development for oncology research.
3. Comparative Analysis
| Feature | CAS 10374-51-3 | Alternative A | Alternative B |
|---|---|---|---|
| Purity Level | 98-99% | 95-97% | 90-92% |
| Thermal Stability | Stable up to 150°C | Degrades at 120°C | Degrades at 100°C |
| Pharma-grade Certification | USP/EP compliant | Industrial grade | Research grade |
4. Industry Case Studies
Case 1: Antiviral API Production
Used in continuous flow synthesis of Tenofovir disoproxil, achieving 92% yield improvement.
Case 2: Oncology Drug Development
Enabled 3x faster chiral separation in kinase inhibitor R&D projects.
5. Client Success Stories
Client A: Top-10 Pharma Company
Reduced production costs by 40% through optimized synthetic routes using our CAS 10374-51-3.
Client B: Biotech Startup
Achieved IND approval 6 months faster using our GMP-grade material for preclinical studies.
6. Inquiry & Technical Support
Contact our experts for:
- Custom synthesis options
- Batch-specific COA requests
- Technical documentation
Email: info@vivalr.com
Phone: (86) 15866781826
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