3-AMINO-ISONICOTINIC ACID METHYL ESTER

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Comprehensive Guide to 3-Amino-Isonicotinic Acid Methyl Ester

Table of Contents

Product Overview & Specifications

3-Amino-Isonicotinic Acid Methyl Ester (CAS 131747-25-6) is a specialized heterocyclic compound widely used in pharmaceutical synthesis and agrochemical research.

Parameter Specification Comparison: Similar Esters
CAS Number 131747-25-6 3-Amino-Benzoic Acid Methyl Ester (CAS 52127-84-3)
Molecular Formula C7H8N2O2 C8H9NO2
Purity ≥98% (HPLC) Typically 95-97% in commercial grades
Solubility Soluble in DMSO, Methanol Limited solubility in polar solvents

Key Applications

Pharmaceutical Intermediates

Critical component in synthesizing anti-tuberculosis agents and kinase inhibitors. Enables precise molecular modifications in lead compound optimization.

Agrochemical Development

Used in creating novel fungicides with improved leaf adhesion and rainfastness properties. Particularly effective against Phytophthora infestans.

Coordination Chemistry

Acts as polydentate ligand in transition metal complexes for catalytic applications and materials science research.

Usage Guidelines

Recommended Protocols

  1. Handling: Use under inert atmosphere (N2 or Ar) for moisture-sensitive reactions
  2. Storage: Maintain at 2-8°C in sealed amber glass containers
  3. Reaction Conditions: Optimal performance at 60-80°C in DMF or THF solvents

Safety Information

Hazard Code Precaution First Aid
Xi Wear nitrile gloves and safety goggles Flush eyes with water for 15 minutes if contacted

Industry Case Studies

Case Study 1: Antiviral Drug Development

Client: European Pharma Research Group
Challenge: Improve bioavailability of NNRTI candidates
Solution: Used as key building block in scaffold modification
Result: Achieved 40% improvement in water solubility

Case Study 2: Next-Gen Fungicides

Client: Global Agrochemical Manufacturer
Challenge: Resistance management in Oomycete pathogens
Solution: Incorporated into novel SDHI fungicide design
Result: 98% efficacy at 50% reduced application rate

Contact for Custom Solutions

Optimize your synthesis with our technical expertise:

Why Choose Our Product?
– Batch-to-batch consistency (RSD <0.5%)
– Custom purity grades (98-99.9%)
– Technical support from PhD chemists

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