5-Bromo-2-methoxy-4-methylpyridine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Basic Parameters
| Parameter | Value |
|---|---|
| Chemical Formula | C₇H₈BrNO |
| Molecular Weight | 218.05 g/mol |
| CAS Number | 107793-53-3 |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Solubility | Soluble in DMSO, methanol, and chloroform |
Comparative Analysis
| Feature | 5-Bromo-2-methoxy-4-methylpyridine | Similar Compounds |
|---|---|---|
| Reactivity | High (due to bromine substituent) | Moderate (e.g., chloro analogs) |
| Stability | Stable under inert conditions | Prone to hydrolysis |
| Synthetic Utility | Wide applicability in cross-coupling reactions | Limited scope |
2. Key Applications
Pharmaceutical Intermediate
Used in synthesizing kinase inhibitors, antiviral agents, and anticancer drugs due to its robust halogen bonding capabilities.
Agrochemical Development
Critical in creating herbicides and fungicides, leveraging its methoxy group for targeted molecular interactions.
3. Usage Scenarios
Scenario 1: Palladium-Catalyzed Cross-Coupling
Employed in Suzuki-Miyaura reactions to construct biaryl structures for drug discovery pipelines.
Scenario 2: Nucleophilic Substitution
Facilitates methoxy group replacement in high-yield nucleophilic aromatic substitutions.
4. Customer Case Studies
Case Study 1: PharmaTech Inc. (USA)
Application: Synthesis of a Bruton’s tyrosine kinase (BTK) inhibitor.
Result: Achieved 92% yield in key coupling step, accelerating preclinical trials.
Case Study 2: AgroChem Solutions Ltd. (Germany)
Application: Development of a novel fungicide targeting wheat rust.
Result: Enhanced bioactivity by 40% compared to previous chloro-based analogs.
5. Request a Quote
Ready to integrate 5-Bromo-2-methoxy-4-methylpyridine into your workflow? Contact our team for tailored solutions:
Email: info@vivalr.com
Tel: (86) 15866781826
Request a free sample or discuss bulk pricing options today.
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