2-Chloro-6-(trifluoromethyl)pyridine

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Table of Contents

Introduction to 2-Chloro-6-(trifluoromethyl)pyridine

CAS No.: 3746-69-0
Molecular Formula: C6H3ClF3N
Appearance: Clear colorless to pale yellow liquid
Purity: ≥98% (GC), ≥99% (HPLC options available)

Critical Quality Parameters

Parameter Standard Grade Premium Grade Pharma Grade
Purity ≥98% ≥99% ≥99.5%
Moisture Content ≤0.5% ≤0.2% ≤0.1%
Chlorinated Byproducts ≤1.0% ≤0.5% ≤0.2%

Technical Specifications & Comparative Analysis

Global Supplier Comparison

Supplier Purity Packaging Lead Time MOQ
Company A 98-99% 25kg/drum 4 weeks 100kg
Company B 99-99.5% Custom packaging 2 weeks 50kg

Key Industrial Applications

Pharmaceutical Intermediate

Used in synthesis of kinase inhibitors for cancer therapeutics. Enables precise functional group positioning in API manufacturing.

Agrochemical Production

Critical intermediate for neonicotinoid insecticides:
– Imidacloprid derivatives
– Sulfoxaflor precursors
Reaction example: C6H3ClF3N + C3H5NO2S → [Intermediate] → Final insecticide

Comprehensive Usage Guidelines

Handling Protocols

  • Storage: Maintain under nitrogen at 2-8°C
  • Reaction Compatibility: Compatible with Pd-catalyzed cross couplings
  • Safety: Use NIOSH-approved respirators when handling powders

Client Case Studies

Case 1: AgroChem Solutions Ltd. (2024)

Challenge: Required high-purity intermediate for EPA-approved insecticide formulation
Solution: Supplied 99.2% purity material with controlled impurity profile
Outcome: Achieved 92% yield in final reaction stage

Case 2: PharmaGen Innovations (2023)

Challenge: Needed GMP-compliant material for Phase III clinical trial
Solution: Custom synthesis with full ICH Q7 documentation
Result: Accelerated FDA submission timeline by 6 weeks

Request Product Samples/Pricing

Contact our technical team:
Email: info@vivalr.com
Phone: (86) 15866781826

Request:
– Technical Data Sheets (TDS)
– Safety Documentation
– Custom Synthesis Options

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