4-Amino-5-bromo-2-chloropyrimidine

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4-Amino-5-bromo-2-chloropyrimidine: Comprehensive Product Guide

1. Product Overview & Specifications

Parameter 4-Amino-5-bromo-2-chloropyrimidine Similar Compounds
CAS Number 1020707-47-5 4-Amino-5-fluoro-2-chloropyrimidine (CAS 89694-91-9)
Molecular Formula C4H3BrClN3 C4H3FClN3
Molecular Weight 237.34 g/mol 175.55 g/mol
Purity ≥98% (HPLC) ≥95%
Melting Point 215-220°C 195-200°C

2. Key Applications & Industry Uses

Pharmaceutical Intermediates

Critical building block for:

  • Kinase inhibitor development (EGFR/VEGFR targets)
  • Anticancer drug candidates
  • Antiviral compound synthesis

Agrochemical Synthesis

  • Herbicide intermediates
  • Fungicide precursors

Advanced Material Science

  • OLED material precursors
  • Coordination complexes for catalysis

3. Performance Advantages

Feature Benefit
Triple Functional Groups Enables diverse derivatization pathways
High Reactivity Superior Suzuki coupling performance vs. chloro analogs
Thermal Stability Maintains integrity under harsh reaction conditions

4. Usage Scenarios & Case Studies

Pharmaceutical Application Example

Scenario: Synthesis of Bruton’s tyrosine kinase (BTK) inhibitor intermediate
Result: 22% yield improvement vs. traditional methods

Agrochemical Implementation

Use Case: Fungicidal carbamate derivative synthesis
Outcome: 15% broader spectrum activity against phytopathogens

5. Client Success Stories

Case 1: ABC Pharmaceuticals

Challenge: Required high-purity intermediate for Phase II oncology drug
Solution: Custom synthesis with >99.5% purity
Impact: Accelerated IND submission by 3 months

Case 2: XYZ AgroChem

Need: Cost-effective fungicide precursor
Delivery: Bulk quantities with 98.7% purity
Result: 30% production cost reduction

6. Request Customized Solutions

Optimize your synthesis pathways with our technical expertise:
Email: info@vivalr.com
Phone: (86) 15866781826

  • GMP-grade production available
  • Custom halogenation patterns
  • Bulk quantities (100kg+ batches)
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