5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidinone

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5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidinone Technical Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Specification
Chemical Formula C19H21N3O2S
Molecular Weight 355.46 g/mol
CAS Number 105355-26-8
Purity Grade ≥98% (HPLC)
Physical Form Off-white crystalline powder
Storage Conditions 2-8°C in airtight container

2. Functional Applications

This thiazolidinone derivative serves as:

  1. Key intermediate in antidiabetic drug synthesis
  2. PPARγ receptor modulator precursor
  3. Research chemical for metabolic syndrome studies
  4. Building block for novel insulin sensitizers

3. Operational Guidelines

Handling Protocols:

  • Use nitrogen atmosphere for sensitive reactions
  • Maintain pH 6.5-7.5 in aqueous solutions
  • Recommended solvent: anhydrous DMF/DMSO

4. Industry Implementation Cases

Pharmaceutical Development:
Used in Phase III clinical trial material for novel T2DM therapeutic (2024-2026)

Academic Research:
Featured in 12 peer-reviewed studies on insulin resistance mechanisms (2023-2025)

5. Client Success Stories

Case 1: European Pharma Leader
Application: Scale-up production of glitazone analogs
Outcome: Achieved 92% yield improvement through optimized synthesis

Case 2: US Research Institute
Application: Development of dual PPAR agonists
Result: Secured NIH funding for preclinical studies

6. Procurement Consultation

For technical specifications, bulk pricing, or custom synthesis requirements:

Contact:
Email: info@vivalr.com
Tel: (86) 15866781826

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