5-Fluoro-2-Methoxy-6-Picoline (CAS No.: 1075198-5F) is a fluorinated pyridine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters include:
| Parameter | Value |
|---|---|
| Molecular Formula | C7H8FNO |
| Molecular Weight | 141.14 g/mol |
| Purity | ≥98% (HPLC) |
| Melting Point | 45-48°C |
| Storage | 2-8°C in airtight container |
Used in the synthesis of kinase inhibitors and antiviral agents due to its electron-withdrawing fluorine group.
Key component in next-gen herbicides with enhanced soil stability and targeted action.
Facilitates metal-organic framework (MOF) development for gas storage applications.
| Compound | 5-Fluoro-2-Methoxy-6-Picoline | 2-Methoxy-6-Picoline | 5-Chloro-2-Methoxy-6-Picoline |
|---|---|---|---|
| Reactivity | High (Fluorine activation) | Moderate | High (Chlorine activation) |
| Synthetic Yield | 82-88% | 75-80% | 78-85% |
| Pharma Compatibility | Excellent | Good | Limited |
Client: Top 10 Global Pharma Company
Challenge: Required high-purity fluorinated intermediate for PI3K inhibitor scale-up.
Solution: Supplied 200kg batches at 99.2% purity under cGMP conditions.
Outcome: Accelerated Phase III trials by 6 months.
Client: EU Agrochem Innovator
Challenge: Needed low-persistence active ingredient meeting EU REACH standards.
Solution: Custom fluorination process achieving 94% degradation in 30 days.
Outcome: Approved in 18 EU markets within 11 months.
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