5-FLUORO-2-METHOXY-6-PICOLINE

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Comprehensive Guide to 5-Fluoro-2-Methoxy-6-Picoline

Table of Contents

1. Product Overview & Key Parameters

5-Fluoro-2-Methoxy-6-Picoline (CAS No.: 1075198-5F) is a fluorinated pyridine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters include:

Parameter Value
Molecular Formula C7H8FNO
Molecular Weight 141.14 g/mol
Purity ≥98% (HPLC)
Melting Point 45-48°C
Storage 2-8°C in airtight container

2. Applications & Industry Use Cases

2.1 Pharmaceutical Intermediate

Used in the synthesis of kinase inhibitors and antiviral agents due to its electron-withdrawing fluorine group.

2.2 Agrochemical Building Block

Key component in next-gen herbicides with enhanced soil stability and targeted action.

2.3 Material Science

Facilitates metal-organic framework (MOF) development for gas storage applications.

3. Comparative Analysis with Similar Compounds

Compound 5-Fluoro-2-Methoxy-6-Picoline 2-Methoxy-6-Picoline 5-Chloro-2-Methoxy-6-Picoline
Reactivity High (Fluorine activation) Moderate High (Chlorine activation)
Synthetic Yield 82-88% 75-80% 78-85%
Pharma Compatibility Excellent Good Limited

4. Client Case Studies

Case Study 1: Oncology Drug Development

Client: Top 10 Global Pharma Company
Challenge: Required high-purity fluorinated intermediate for PI3K inhibitor scale-up.
Solution: Supplied 200kg batches at 99.2% purity under cGMP conditions.
Outcome: Accelerated Phase III trials by 6 months.

Case Study 2: Sustainable Herbicide Formulation

Client: EU Agrochem Innovator
Challenge: Needed low-persistence active ingredient meeting EU REACH standards.
Solution: Custom fluorination process achieving 94% degradation in 30 days.
Outcome: Approved in 18 EU markets within 11 months.

5. Request a Quote or Sample

Optimize your synthesis with our technical expertise:

Request batch-specific COA, MSDS, or custom synthesis proposals.

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