Methyl tetrahydropyran-4-carboxylate

Table of Contents

• Product Overview
• Specifications & Comparative Analysis
• Applications
• Usage Guidelines
• Case Studies
• Contact for Technical Support

Methyl Tetrahydropyran-4-Carboxylate Overview

CAS No.: 942195-03-1
Molecular Formula: C₈H₁₂O₃
Molecular Weight: 156.18 g/mol
Methyl tetrahydropyran-4-carboxylate is a high-purity ester derivative widely used as a versatile intermediate in pharmaceuticals, agrochemicals, and specialty chemical synthesis. Its tetrahydropyran ring structure enhances stability and reactivity in nucleophilic reactions.

Specifications & Comparative Analysis

Key Applications

Pharmaceutical Industry

• Intermediate for antiviral drugs (e.g., protease inhibitors)
• Chiral building block in CNS drug development

Agrochemicals

• Synthesis of herbicidal compounds
• Stabilizer in pesticide formulations

Usage Guidelines

Laboratory Scale

1. Recommended storage: 2-8°C under inert gas
2. Use anhydrous conditions for coupling reactions

Industrial Scale

1. Batch reactor compatibility: Glass-lined or Hastelloy
2. Optimal reaction temperature range: 40-80°C

Case Studies

Case 1: Antiviral Drug Intermediate Synthesis

Client: Top 10 Global Pharma Company (Confidential)
Application: Used in 3-step synthesis of Remdesivir analogue
Result: 22% yield improvement vs. previous intermediates

Case 2: Chiral Catalyst Development

Client: University of Cambridge Research Group
Application: Key component in asymmetric hydrogenation catalysts
Result: Achieved 95% enantiomeric excess (ee)

Technical & Commercial Inquiry

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