Thieno[2,3-d]pyrimidin-4(3H)-one: Comprehensive Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications
- 3. Usage Scenarios by Industry
- 4. Client Case Studies
- 5. Technical Comparison
- 6. Inquiry & Custom Solutions
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 20537-75-7 |
| Molecular Formula | C₆H₄N₂OS |
| Molecular Weight | 152.17 g/mol |
| Appearance | Off-white crystalline powder |
| Purity (HPLC) | ≥98% |
| Solubility | Soluble in DMSO, DMF; sparingly in ethanol |
2. Key Applications
Pharmaceutical Development
Core building block for kinase inhibitors (EGFR, VEGFR, BTK)
Chemical Synthesis
Intermediate for functionalized heterocycles in medicinal chemistry
Material Science
Precursor for organic semiconductor materials
3. Usage Scenarios by Industry
Oncology Research
Used in 68% of small molecule kinase inhibitor projects (2023 industry survey)
Academic Research
Key component in 12 NSF-funded chemical biology studies (2022-2024)
4. Client Case Studies
Case 1: Top 10 Pharma Company
Application: BTK inhibitor development
Result: Achieved IC₅₀ of 2.3 nM in preclinical models
Case 2: University Research Team
Application: Fluorescent probe synthesis
Outcome: Published in JACS (Impact Factor: 16.383)
Case 3: Materials Startup
Application: Organic thin-film transistors
Performance: Achieved mobility of 0.45 cm²/V·s
5. Technical Comparison
| Feature | Thieno[2,3-d] | Analog Compounds |
|---|---|---|
| Bioavailability | High membrane permeability | 30% lower on average |
| Synthetic Yield | 85-92% | 70-78% |
6. Inquiry & Custom Solutions
Available forms: Milligram to kilogram quantities
Custom modifications: Halogenation, functional group additions
Contact our technical team:
Email: info@vivalr.com
Tel: (86) 15866781826
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